we aimed to study the mntnhex-2-pyp effect on some markers of lung antioxidant defence system in mice asthma model.the study was carried out on 28 c57b1/6 mice divided into four treatment groups: group 1 - controls; group 2 - injected and inhaled with ovalbumin; group 3 - treated with mntnhex-2-pyp and inhaled with phosphate buffered saline; group 4 - injected with ovalbumin and mntnhex-2-pyp b...

PURPOSE Diabetic retinopathy (DR) is characterized by increased oxidative and nitrosative stress, both of which lead to neurotoxicity and vascular permeability. Previous studies on a variety of organs indicate that hydrogen-rich saline not only has considerable antioxidant and anti-inflammatory properties, but also suppresses oxidative stress-induced injury. In the present study, we assessed th...

Oxidative stress plays an important role in the pathogenesis of acute pancreatitis (AP). As an ideal exterminator of poisonous free radicals, hydrogen can clearly reduce the degree of oxidative damage caused by severe acute pancreatitis (SAP) and lessen the presence of inflammatory cytokines. The aim of this study was to investigate the effects and mechanism of hydrogen-rich saline on SAP in ra...

Since N-acetylcysteine (NAC) is a donor of cysteine, we studied the relationship between NAC and concentration of oxidized and reduced glutathione (GSH/GSSG ratio), and glutathione peroxidase (GPx) and glutathione-S-transferase (GST) activities in the lumbosacral spinal cord of rats with chronic constriction injury (CCI) of the sciatic nerve that received NAC (150mg/kg/day, i.p.) or 0.9% saline...

background: the aim of the present study was to evaluate the radioprotective effect of grewia asiatica fruit pulp extract (gae) on swiss albino mice exposed to gamma radiation. in the present study radioprotective efficacy of grewia asiatica (rich in anthocyanin, carotenes, vitamin c, etc.) was studied against radiation induced biochemical alterations in mice cerebrum. materials and methods: fo...