It is still not completely clear whether carbamazepine causes alterations in vitamin D status and in bone metabolism. Th e objective of this study was to investigate the eff ects of carbamazepine on serum levels of -hydroxyvitamin D and on biomarkers of bone formation and resorption in healthy rats. Levels of calcium, hydroxyvitamin D, parathormone, C-telopeptide, bone specifi c alkaline ph...

It is still not completely clear whether carbamazepine causes alterations in vitamin D status and in bone metabolism. The objective of this study was to investigate the effects of carbamazepine on serum levels of 25-hydroxyvitamin D and on biomarkers of bone formation and resorption in healthy rats. Levels of calcium, 25- hydroxyvitamin D, parathormone, C-telopeptide, bone specific alkaline pho...

CYP3A4 probably has the broadest catalytic activity of any cytochrome P450. It is a crucial task to test new drug candidates in a reliable system for their ability to induce expression of this enzyme. Firstly, a total of 300 bp core distal enhancer of CYP3A4 XREM region (-7972/-7673) were amplified from human genomic DNA. The PCR product was then ligated into a human secretory alkaline phosphat...

Soil correction is one of the ways in agriculture lands development. The sodic ion alongside salin vocalizes the salin-sodic soil and cause divulge in plants growth. So necessary coure of action for the Soil correction by physical and chemical ways such as usage of calsium on the leaching is inevitable. In this study, area soils are digged from deep profiles of 0-20, 20-40, 40-60, 60-80 and 80-...

Background: Acantholimon gilliati Turril(Plumbaginaceae) is used in variety of diseases including hepatic ailments in the west region of Iran. Aim of the study: To investigate the hepatoprotective effect of methanoilc extract (ME) of A. gilliati on formaldehyde (FA) induced liver injury in adult male mice.Materials and methods: Fifty six adult male mice were divided into 8 groups. In control gr...