Erythromycin ophthalmic ointment (E. Fougera & Co., Melville, N.Y.) and erythromycin gluceptate standards prepared in ointment base were stored at room temperature and heated at temperatures up to 45 degrees C for as long as 6 h before being assayed for bioactivity. We were unable to detect any significant loss of antibiotic bioactivity.

background: this two-arm, randomized clinical study aimed to compare efficacy between topical alpha ointment and topical hydrocortisone cream (1%) in the healing of radiation-induced dermatitis in breast cancer patients. methods: the inclusion criteria comprised newly pathologically proven, locally advanced breast cancer (treated with modified radical mastectomy followed by sequential adjuvant ...

Haemorrhoids, caused by the inflammation and symptomatic enlargement of anal cushions, are a common pathological condition. The conventional medical treatment haemorrhoids shares similarities with Arsoroga in Ayurveda, both terms etiology clinical features. Kankayana Vati is widely used internal medicine for haemorrhoids, although dosage has not been explicitly specified. Additionally, novel oi...

background: a common, early postpartum concern of the breastfeeding mother is nipple pain. because of a lack of effective treatment and opposing results about lanolin, we decided to compare the effect of lanolin ointment and aloe vera gel on nipple soreness treatment. methods: this clinical blind trial was performed in mashhad, iran, from february 2008 to may 2009. sampling was nonrandom and pu...

St John's wort (Hypericum perforatum) is a traditional herbal medicine that is used for the topical treatment of superficial wounds, burns and dermatitis. The characteristic metabolites of St John's wort are the photodynamic active plant pigment hypericin and the phloroglucin-derivative hyperforin. To date, no studies on immunomodulatory properties of topical preparations of St John's wort have...

BACKGROUND Tacrolimus ointment is increasingly used for anti-inflammatory treatment of sensitive areas such as the face, and recent observations indicate that the treatment is effective in steroid-aggravated rosacea and perioral dermatitis. We report on rosaceiform dermatitis as a complication of treatment with tacrolimus ointment. OBSERVATIONS Six adult patients with inflammatory facial derm...

OBJECTIVE The purpose of this study was to evaluate the risk of cutaneous infection in patients with atopic dermatitis treated with tacrolimus ointment. METHODS Data for 1554 patients with atopic dermatitis, treated with tacrolimus ointment in 5 clinical trials, were analyzed. RESULTS In 3 controlled studies, the 12-week adjusted incidence of all cutaneous infections in patients treated wit...

Objective Painful nipple fissure is a troublesome problem for breastfeeding mothers. This study was conducted to evaluate the effect of saqez (Pistacia atlantica) ointment on the improvement of nipple fissure in breastfeeding women during one-month follow-up. Materials and Methods This randomized controlled clinical trial was conducted on 100 eligible women who visited the selected health cen...

Introduction. This study compared the healing efficacy and possible adverse effects of topical Alpha and medical-grade honey ointments on cutaneous wounds in rats. Methods. To conduct the study, 22 male Sprague-Dawley rats were randomly allocated into two equal groups: (1) rats with Alpha ointment applied to the wound surface area and (2) rats with medical-grade honey ointment applied to their ...

As has been shown previously, phosphite of acycloguanosine (Hp-ACG) exhibits equal efficacy against ACV-sensitive and ACV-resistant HSV-1 strains in cell culture. Intraperitoneal administration of Hp-ACG to model mice with herpetic encephalitis caused by HSV-1 infection was shown to be effective in protecting against death. In the present work, we continue the study of the antiviral efficiency ...