نتایج جستجو برای: saab

تعداد نتایج: 198  

1999
Simin Nadjm-Tehrani

The synchronous family of languages (Lustre, Esterel, Signal , Statecharts) provide a great deal of support for verifying a control program at the design and compilation stage. However, a common aspect of embedded systems is that signiicant properties of the system can not be veriied by formally analysing the controller (software) on its own. To analyse the system one requires to state and docu...

2007
D. Luseba E. E. Elgorashi D. T. Ntloedibe J. Van Staden

Crude dichloromethane and 90%methanolic extracts of plants used traditionally in the treatment of wounds and retained placenta were screened for their antibacterial, anti-inflammatory (cyclooxygenase-1 and-2) activities and investigated for potential mutagenic effects. Antibacterial activity was evaluated using the micro-dilution assay. The bacterial strains used were Staphylococcus aureus (ATC...

Journal: :Annals of Oncology 2022

Regorafenib is an oral multikinase inhibitor approved for advanced mCRC, gastrointestinal stromal tumors, and hepatocellular carcinoma. The phase 2 regorafenib dose-optimization study (ReDOS; Bekaii-Saab TS, et al., 2019) demonstrated that patients could initiate at a dose of 80 mg/day then subsequently escalate their depending on tolerability without compromising efficacy. In March 2018, the R...

2009
Tanios Bekaii-Saab Joseph Markowitz Nichole Prescott Wolfgang Sadee Nyla Heerema Lai Wei Zunyan Dai Audrey Papp Angela Campbell Kristy Culler Catherine Balint Bert O'Neil Ruey-min Lee Mark Zalupski Janet Dancey Helen Chen Michael Grever Charis Eng Miguel Villalona-Calero

Background: Hepatocellular carcinoma (HCC) is on the rise worldwide. HCC responds poorly to chemotherapy. Lapatinib is an inhibitor of epidermal growth factor receptor and HER2/NEU both implicated in hepatocarcinogenesis. This trial was designed to determine the safety and efficacy of lapatinib in HCC. Methods: A Fleming phase II design with a single stage of 25 patients with a 90% power to exc...

Journal: :Heart, lung & circulation 2015
Jialiang Chin Jordan Fulcher Alicia Jenkins Anthony Keech

OBJECTIVES Optimising secondary prevention of cardiovascular disease has the greatest potential to reduce recurrent events, yet despite major guidelines there are ongoing treatment gaps. FFSAABC (Fish oils, Fibrates, Statins, Aspirin, Angiotensin converting enzyme inhibitors or angiotensin 2 receptor antagonists, Beta blockers and Clopidogrel) is one mnemonic previously adopted to assist clinic...

2008
Karin Bredin

This doctoral thesis addresses human resource management in project-based organisations. The aim is to explore the challenges for HRM in project-based organisations and the changes in people management systems to meet these challenges. The thesis consists of a compilation of six papers and an extended summary. The research reported in the thesis is based on a combination of multiple-, comparati...

2008
P. M. Tilney B.-E. Van Wyk S. R. Downie C. I. Calviño

Evolutionary relationships within the poorly known and anomalous South African endemic genus Lichtensteinia were elucidated. Phylogenetic analysis of morphological and anatomical characters suggests that there are two main groups of species, viz. the L. obscura–L. globosa–L. interrupta (including L. kolbeana) clade and the L. latifolia–L. trifida–L. lacera–L. crassijuga clade. Furthermore, Lich...

Journal: :Aviation, space, and environmental medicine 1998
T K Leino J Leppäluoto A Ruokonen P Kuronen

METHODS To investigate the influence that psychological workload, associated with simulated combat military flight, has on secretion of stress hormones we measured concentrations of plasma corticotropin-releasing hormone (CRH), pro-opiomelanocortin (POMC) related adrenocorticotropin (ACTH), beta-endorphin (BE), and cortisol in 10 Finnish Air Force (FAF) military interceptor pilots. They perform...

2010
C. J. Majetic M. D. Rausher R. A. Raguso

Many recent studies attempting to assess the biochemical connections between anthocyanin biosynthesis and floral scent production have yielded limited insights due in part to a focus on either field phenotypes of unknown genetic background or artificial genetic manipulation. In this study, we seek to more precisely explore the mechanistic connections between floral scent and color in Ipomoea pu...

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