background: cushing's disease is the most prevalent cause of endogenous adrenocorticotrophic hormone hypersecretion. the aim of this study was to document the current clinical practice pattern in the management of cushing's disease by iranian endocrinologists to determine their opinions and compare them with the current clinical practice guidelines.    methods: an eight-item questionnaire deali...

background current surgical treatments in peyronie's disease are accompanied by complications such as penile shortening, loss of sensation, erectile dysfunction and recurrence of disease. the aim of this study was the evaluation of clinical results of intracavernosal plaque excision in peyronie's disease. methods the operation was performed on 35 men. it was consisted of incising the ...

conclusions these data suggest that single bilateral microinjection of aβ (25-35) could impair memory and can be used as an ad model in wistar rats. results the results showed that aβ (25-35) significantly impaired both step-through latency and time in dark compartment in the passive avoidance task. background alzheimer's disease (ad) is the most common form of dementia that leads to neurotoxic...

different treatment strategies of alzheimer's disease (ad) are being studied for treating or slowing the progression of ad. many pharmaceutically important regulation systems operate through proteins as drug targets. here, we investigate the drug target proteins in beta-amyloid (aβ) injected rat hippocampus treated with lavandula angustifolia (la) by proteomics techniques. the reported stu...

objective: to investigate the correlation between lower and higher order sensory functions and manual dexterity as well as to identify the sensory measures that could predict manual dexterity in patients with idiopathic parkinson’s disease (pd). materials and methods: in this cross-sectional study, 55 patients with idiopathic pd by mean age of 59.85 ± 11.89 years, and mean hoehn and yahr stage ...

background alzheimer's disease (ad) is the most common type of dementia. patients with ad have impaired semantic knowledge of nouns and verbs as well as the ability to verb retrieval. objectives the aim of this study was to compare verbal fluency and verb fluency and to investigate the association between severity and types of fluency (verbal-verb) in patients with ad. patients and methods this...

behcet´s disease (bd) is accepted as a systemic vasculitis. vasculitis is observed  predominantly on the venous system. vessel involvement is frequently seen in males. this study was planned retrospectively evaluate demographic features, clinical features, vessel involvements in bd. furthermore, we aimed to prospectively compare consecutively chosen patients with and without thrombosis and heal...

castleman's disease is an uncommon cause of lymph node enlargement that mostly involves the mediastinum and lung hilum. it is divided into 2 types: localized, which is usually asymptomatic and presents with a mass lesion; and multicentric, which is characterized by chills, anemia, generalized lymphadenopathy and hepatosplenomegaly. an extrathoracic site of involvement is very uncommon, and may ...

marek's disease (md) is a common lymphoproliferative disease of chickens, usually characterized by mononuclear cellular infiltration in different organs. the disease is caused by a herpes virus and is transmissible. md has been a common, important problem for poultry industry worldwide, as well as, in our country, iran. the aim of present study was to have an estimation of the incidence of...

background: vitamin d is an important factor responsible for many physiologic functions. vitamin d deficiency is associated with increased risk of neurodegenerative disease. the level of vitamin d in iranian patients with parkinson's disease and its relationship with severity of symptoms and signs were evaluated in this study. methods: eighty-three patients with parkinson's disease (pd) were re...