polyacrylonitril (pan)-supported chitosan (cs) nanocomposite membranes were prepared by cross-linking the cs with 3-aminopropyl-triethoxysilane (apteos) via sol-gel method. pervaporative performances of the cs-sio2/pan membrane for dehydration of aqueous alcohol solutions were investigated. from sem cross-sectional images of the membrane, the spongy pores and the finger-like pores were found in...

the aim of this study was to design orally disintegrating tablets of olanzapine and to complex olanzapine with 2-hydroxypropyl-β- cyclodextrin with special emphasis on disintegration and dissolution studies. phase solubility studies demonstrated the formation of 1:1 molar inclusion complex by kneading method. tablets were prepared by using superdisintegrants namely, sodium starch glycolate, cro...

objective(s):several investigations have revealed that caspase-14 is responsible for the epidermal differentiation and cornification, as well as the regulation of moisturizing effect. however, the precise regulation mechanism is still not clear. this study was aimed to investigate the expression of caspase-14 in filaggrin-deficient normal human epidermal keratinocytes (nheks) and to explore the...

improving the processing and the recycled paper properties is one of permanent concern of papermaking. in this research, the effect of nanochitosan addition on the process and product quality made of writing and printing recycled fiber was investigated. being nano size and so its capability in access to the space between pulp suspension components and also its probable ability to make electrost...

the oxidation of low-density lipoproteins and cell membrane lipids is believed to play an integral role in the development of fatty streak lesions, an initial step in coronary artery disease (cad). paraoxonase-1 (pon1) is an enzyme associated with the high-density lipoprotein (hdl) particle. pon1 protects ldl from oxidative modification by hydrolyzing lipid peroxides, suggestive of a role for p...

the aim of this study was to examine the anti-inflammatory effects of co-administration of growthhormone-releasing peptide-2 (ghrp-2) and growth hormone (gh) on tumor necrosis factor-α (tnf-α),interleukin-6 (il-6) and inducible nitric oxide synthase (inos) gene expression induced by lps in the mousebrain. thirty-five male nmri mice (25±5 g) were injected through the mouse tail vein with saline,...