Green nail syndrome (chromonychia) is a nail disorder characterized by onycholysis and green-black discoloration of the nail bed. This condition is often associated with chronic paronychia. Pseudomonas aeruginosa is the most commonly identified organism in cultures from the affected area. Despite the various treatment options available, removal of the nail is still necessary in many cases. A 35...

BACKGROUND Nail bed injuries account for the majority of paediatric hand trauma cases. Despite their frequency, controversy remains regarding their treatment. The accepted teaching is to remove the fingernail, repair the underlying nail bed with fine sutures and replace the nail under the nail fold. A recent study by Miranda et al. (Plast Reconst Surg. 129(2):394e-396e, 2012) suggests that repl...

2289. A Multicenter Study of the Clinical and Molecular Epidemiology of TEMand SHV-type ExtendedSpectrum β-Lactamase producing (ESBL) Enterobacteriaceae (Ent) Infections in Children Jared R. Rispens, MD; Rachel L. Medernach, MD; Andrea M. Hujer, BS; T. Nicholas Domitrovic, BA; Steven H. Marshall, MS; Susan D. Rudin, BS; Xiaotian Zheng, MD, PhD; Nadia K. Qureshi, MD; Mary K. Hayden, MD, FIDSA, F...

It is f i t t ing in this b icentennial year of the United States, for the ed i f i ca t ion of oncologists, to cast a glance at what physicians o f the American Revolut ion though t and practiced about cancer . There is no better source of such en l igh tenment than the wri t ings o f Benjamin Rush (1745-1813) of Phi ladelphia. Of English Quaker stock, born in Pennsylvania and educated at Pr i...

This book is a collection of new essays around the broad central theme of the nature of logic, or the question: ‘what is logic?’ It is a book about logic and philosophy equally. What makes it unusual as a book about logic is that its central focus is on metaphysical rather than epistemological or methodological concerns. By comparison, the question of the metaphysical status of mathematics and ...

Knowledge of the anatomy and function of the nail apparatus is essential when performing the physical examination. Inspection may reveal localized nail abnormalities that should be treated, or may provide clues to an underlying systemic disease that requires further workup. Excessive keratinaceous material under the nail bed in a distal and lateral distribution should prompt an evaluation for o...

License to glue eplication of DNA and cohesion of the resultant sister chromatids are two activities that must be coordinated. found that the same " licensing " process that gets DNA ready for replication is also necessary to allow loading of the cohesin complex responsible for sister chromatid cohesion. Gillespie and Hirano used the sequence of yeast cohesin-loading proteins to identify human ...

IMPORTANCE Nail psoriasis can be difficult to treat and has a significant effect on quality of life. Relatively few controlled trials evaluating treatments for nail psoriasis have been published. There is an unmet need for treatment recommendations to guide therapeutic decisions. OBJECTIVE To develop treatment recommendations for nail psoriasis from the Medical Board of the National Psoriasis...

BACKGROUND The nail gun is a commonly utilized tool in carpentry and construction. When used properly with appropriate safety precautions, it can facilitate production and boost efficiency; however, this powerful tool also has the potential to cause serious injury. The most common site of nail-gun injuries in both industrial and nonoccupational settings is the hand. MATERIALS AND METHODS We r...

Objective To present family physicians with common nail alterations and disorders occurring in the elderly population and their management options. Quality of evidence The evidence relating to different nail conditions is mostly derived from randomized controlled trials, meta-analyses, and review articles. However, given the scarcity of evidence on some conditions, articles with weaker levels o...