OBJECTIVE Type 2 diabetes is a risk factor for other forms of stroke, but its association with subarachnoid hemorrhage (SAH) from ruptured saccular intracranial aneurysm (sIA) has remained unclear. RESEARCH DESIGN AND METHODS Kuopio Intracranial Aneurysm Database (www.uef.fi/ns) includes all ruptured and unruptured sIA cases from a defined catchment population in eastern Finland since 1980. W...

Objectives To identify the risk factors for postoperative renal dysfunction after open surgical repair (OSR) of abdominal aortic aneurysms (AAAs) and to establish a scoring system. Results The overall 30-day mortality rates were 22.0%(ruptured) vs 2.6% (unruptured), respectively. For the ruptured group, the independent risk factors were hemodynamic instability (P = 0.002) blood loss >1 L (P =...

Background: Intracranial aneurysm (IA) is a common vascular disease which causes neoplastic hyperplasia of cerebral vessels. It is very important to study relevant factors that influence the prognosis of patients with ruptured intracranial aneurysm to guide the clinical treatment of IA. Methods: This study made a retrospective analysis on data of 580 patients with ruptured IA. To screen risk fa...

BACKGROUND AND PURPOSE Rupture of atherosclerotic plaques is one of the main causes of ischemic strokes. The aim of this study was to investigate carotid plaque vulnerability markers in relation to blood flow direction and the mechanisms leading to plaque rupture at the upstream side of carotid stenoses. METHODS Frequency and location of rupture, endothelial erosion, neovascularization, and h...

BACKGROUND AND PURPOSE The risk of intraprocedural aneurysm perforation in patients with previously ruptured aneurysms tends to be higher than that of patients with previously unruptured aneurysms, but a statistically significant difference has not been shown. Our purpose was to define the rates of occurrence and of morbidity and mortality associated with aneurysmal perforation associated with ...

PURPOSE The purpose was to evaluate the incidence and risk factors for rebleeding during cerebral angiography in ruptured intracranial aneurysms. MATERIALS AND METHODS Among 1896 patients with ruptured intracranial aneurysms between September 2006 and December 2013, a total of 11 patients who experienced rebleeding of the ruptured aneurysms during digital subtraction angiography (DSA) were re...

BACKGROUND Abdominal aortic aneurysm (AAA) expansion is characterized by extracellular matrix degradation and widespread inflammation. In contrast, the processes that characterize AAA rupture are not well understood. The aim of this study was to investigate the proteolytic and cellular activity of ruptured AAA, focusing on matrix metalloproteinases (MMPs) and their inhibitors (TIMPs). METHODS...

Jet action from experimental "berry" aneurysms was evaluated as part of a long-range study of stress-strain-time relations of aneurysmal rupture. It was apparent that free jet action was a potent stress agent upon matter in its path. Calculated velocities of free jets ranged up to 477 cm. per sec. Supplementary observations were made upon jets from glass-model aneurysms, including the jet effec...

A pure posteriorly posterior communicating artery (PCoA) aneurysm represents a surgical challenge. This is mainly when there need for good exposure of the aneurysmal neck, sac, PCoA, and anterior choroidal arteries. Ruptured directed PCoA imposes significantly extra challenge as surgeon undergoes dissection through tight brain. Even with measures commonly used to attain brain relaxation like lu...

Ruptured de novo aneurysms, compared with the usual subarachnoid hemorrhage, commonly occur in younger patients and are extremely rare in elderly patients. We discuss their etiology and report the case of a ruptured de novo aneurysm in a 77-year-old woman.