نتایج جستجو برای: runt

تعداد نتایج: 986  

Journal: :Blood 2000
Y Imai M Kurokawa K Izutsu A Hangaishi K Takeuchi K Maki S Ogawa S Chiba K Mitani H Hirai

The AML1 gene encodes a DNA-binding protein that contains the runt domain and is the most frequent target of translocations associated with human leukemias. Here, point mutations of the AML1 gene, V105ter (single-letter amino acid code) and R139G, (single-letter amino acid codes) were identified in 2 cases of myelodysplastic syndrome (MDS) by means of the reverse transcriptase-polymerase chain ...

2015
Atul P. Daiwile Saravanadevi Sivanesan Alberto Izzotti Amit Bafana Pravin K. Naoghare Patrizio Arrigo Hemant J. Purohit Devendra Parmar Krishnamurthi Kannan

Fluorosis is caused by excess of fluoride intake over a long period of time. Aberrant change in the Runt-related transcription factor 2 (RUNX2) mediated signaling cascade is one of the decisive steps during the pathogenesis of fluorosis. Up to date, role of fluoride on the epigenetic alterations is not studied. In the present study, global expression profiling of short noncoding RNAs, in partic...

Journal: :American Journal of International Law 2022

Abstract Having recently emerged from its unenviable status as the runt of international law, phenomenon statelessness nonetheless eludes traditional legal instruments. Confronted with questions nationality that typically fall within domain sovereignty, and regional human rights bodies struggle to rein in increasingly creative measures states adopt obscure production persistence statelessness. ...

Journal: :Biocell 2023

Runt-related transcription factor-1 (RUNX1), also known as the core-binding factor alpha 2 subunit, is closely related to human leukemia. The functions of RUNX1 in modulating cell proliferation, differentiation, and survival multiple systems have been gradually discovered with emergence transgenic mice. a powerful implicated diverse signaling pathways cellular mechanisms that participate lung d...

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