نتایج جستجو برای: rtk

تعداد نتایج: 2049  

2010
Peter J.G. Teunissen Dennis Odijk Baocheng Zhang

During the last decade the technique of CORS-based Network RTK has been proven capable of providing cm-level positioning accuracy for rovers receiving GNSS correction data from the CORS network. The technique relies on successful integer carrier-phase ambiguity resolution at both network and user level: at the level of the CORS network, ambiguity resolution is a prerequisite in order to determi...

Journal: :The Journal of clinical investigation 2011
Hiromichi Ebi Ryan B Corcoran Anurag Singh Zhao Chen Youngchul Song Eugene Lifshits David P Ryan Jeffrey A Meyerhardt Cyril Benes Jeffrey Settleman Kwok-Kin Wong Lewis C Cantley Jeffrey A Engelman

Therapies inhibiting receptor tyrosine kinases (RTKs) are effective against some human cancers when they lead to simultaneous downregulation of PI3K/AKT and MEK/ERK signaling. However, mutant KRAS has the capacity to directly activate ERK and PI3K signaling, and this is thought to underlie the resistance of KRAS mutant cancers to RTK inhibitors. Here, we have elucidated the molecular regulation...

2014
Ahmed El-Mowafy

In the classic RTK method using a single reference station the rover needs to work within a short range from the reference station due to the spatial decorrelation of distance-dependent errors induced by the ionosphere, troposphere and orbital errors. The operating range of RTK positioning is thus dependent on the existing atmospheric conditions and is usually limited to a distance of up to 10-...

2008
Marcin Uradzinski

Current fast and reliable Internet services provide many advantages for worldwide GNSS users. Development of techniques using the Internet for streaming RTK/DGPS corrections allows mobile users to achieve high-accuracy positioning over both short and long baselines. Applications like GNSS Internet Radio are used for distributing raw GPS data and real-time corrections of GPS observations via RTC...

2015
Xue-Ru Wu Cathy Mendelsohn David J. DeGraff

Although bladder cancer (BC) was the cancer from which the first human oncogene, RAS, was identified, questions persisted over the past 35 years as to whether RAS activation in urothelium was tumorigenic [1]. This was due in large part to the relatively low frequency (~15%) and lack of grade and stage association of RAS mutations in human BC [2]. However, the tide is turning recently in favor o...

2005
Craig Roberts C. Roberts

GPS technology, in particular real-time kinematic (RTK) GPS, has matured to the stage where it has become another tool for the professional surveyor. Commercial products offer user-friendly hardware/software and suggest techniques that can improve productivity at a high accuracy. Government services such as SCIMS in NSW and AUSPOS (Geoscience Australia) support improved GPS positioning and surv...

2002
Fernando Roch Gerardo Jiménez Jordi Casanova

Activation of receptor tyrosine kinases (RTKs) by secreted growth factors regulates cell proliferation and cell fate determination in many different cellular and developmental contexts. Despite such widespread functions, RTK signalling involves a common cytoplasmic cascade including Ras, and the serine-threonine kinases Raf, MAPKK/MEK and MAPK. Thus, a central issue is how activation of the sam...

2011
Guoan Zhang Thomas A. Neubert

There are three quantitative phosphoproteomic strategies most commonly used to study receptor tyrosine kinase (RTK) signaling. These strategies quantify changes in: (1) all three forms of phosphosites (phosphoserine, phosphothreonine and phosphotyrosine) following enrichment of phosphopeptides by titanium dioxide or immobilized metal affinity chromatography; (2) phosphotyrosine sites following ...

2012
Davut KARAYEL Mehmet TOPAKCI Ilker UNAL Egidijus ŠARAUSKIS Murad CANAKCI

We investigated the potential use of real-time kinematic (RTK) global positioning system (GPS) to determine seedling distribution and plant growing area mapping by evaluating the obtained level of accuracy. High-accuracy seed and plant growing area mapping can potentially be used in the evaluations of seeding machine performance, weed control, and plant-specific crop management. Actual plant lo...

2018
James W Peacock Ario Takeuchi Norihiro Hayashi Liangliang Liu Kevin J Tam Nader Al Nakouzi Nastaran Khazamipour Tabitha Tombe Takashi Dejima Kevin Ck Lee Masaki Shiota Daksh Thaper Wilson Cw Lee Daniel Hf Hui Hidetoshi Kuruma Larissa Ivanova Parvin Yenki Ivy Zf Jiao Shahram Khosravi Alice L-F Mui Ladan Fazli Amina Zoubeidi Mads Daugaard Martin E Gleave Christopher J Ong

Growth factor receptor tyrosine kinase (RTK) pathway activation is a key mechanism for mediating cancer growth, survival, and treatment resistance. Cognate ligands play crucial roles in autocrine or paracrine stimulation of these RTK pathways. Here, we show SEMA3C drives activation of multiple RTKs including EGFR, ErbB2, and MET in a cognate ligand-independent manner via Plexin B1. SEMA3C expre...

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