Consider the standard multiple testing problem where many hypotheses are to be tested, each hypothesis is associated with a test statistic, and large test statistics provide evidence against the null hypotheses. One proposal to provide probabilistic control of Type-I errors is the use of procedures ensuring that the expected number of false positives does not exceed a user-supplied threshold. A...

OBJECTIVE To evaluate surgical techniques, perioperative complications and outcome of laparoscopic surgery for unilateral and bilateral ovariectomy in mares. STUDY DESIGN Retrospective multicenter case series. ANIMALS Mares (n = 157). METHODS Indications for surgery were neutering, fertility problems, elimination of hormone-related abnormal behavior, ovarian tumors as well as nonregressiv...

In the 1970s, Semm developed thermocoagulation, adapted the Roeder Loop, and further invented extra- and intracoporeal endoscopic knotting to achieve endoscopic hemostasis. His numerous technical inventions, especially the electronic insufflator, allowed more complex operations to be performed laparoscopically. His technique, however, was not quickly adopted by the surgical community. When the ...

In the work described in this paper, a method has been developed for direct microscopic observation of the smaller blood vessels of the mammalian lung in the unopened thorax. The behavior of these vessels and the flow of blood through them have been studied under a variety of conditions. We were particularly interested in their normal behavior, in the question of intermittence of the flow of bl...

INTRODUCTION Acute appendicitis is the most common abdominal pathology requiring emergent surgical procedure. For treatment, laparoscopic surgery is commonly performed. For appendix stump closure different procedures are used. AIM Evaluation of the results of patients in whom the stump of the appendix was closed with a hand-made loop during laparoscopic appendectomy (LA). MATERIAL AND METHO...

During the 1950s through the 1970s, Hans Orthner and Fritz Roeder, two German neurologists from Göttingen, developed a sophisticated technique to perform functional stereotactic surgery with outstanding accuracy. They introduced direct air ventriculography performed in the same surgical session as the ablative stereotactic procedure. For individualized surgical targeting, Orthner prepared a ste...

(n ! 2). In all cases, histological examination indicated normal spermatogenesis. We analyzed karyotypes and conducted STS-based assays for Yq microdeletions on eight individuals and detected no abnormalities. Seminiferous tubules were prepared for immunolocalization and fluorescence in situ hybridization (FISH) as described (5). We conducted standard immunostaining (23) with CREST antiserum to...

The propagation of light through a Universe of (a) isothermal mass spheres amidst (b) a homogeneous matter component, is considered. We demonstrate by an analytical proof that as long as a small light bundle passes through sufficient number of (a) at various impact parameters-a criterion of great importance-its average convergence will in the weak lensing limit exactly compensate the divergence...