To date, there is no consensus regarding the influence of different CD45 isoforms during peripheral B-cell development. Examining correlations between surface CD45RO expression and various physiologic processes ongoing during the germinal center (GC) reaction, we hypothesized that GC B cells, like T cells, that up-regulate surface RO should progressively acquire phenotypes commonly associated w...

Samosir is an island in North Sumatra which used as a tourist destination because of the beauty its lake. Crossing to requires ship sea transportation. Based on data from Ministry Transportation, Ajibata Port, process crossing vehicles holidays has been delayed due surge passengers during high season. The purpose this research design/plan overcome accumulation number method comparison method. s...

As part of the FIRESAFE II project commissioned by European Maritime Safety Agency a study was performed to determine safe distance between side openings and Life-Saving Appliances (LSA) in ro-ro spaces keep them available usable for evacuation. The utilised analytical calculations CFD simulations. Two exclusion zones, where LSA should not be placed, were defined. first zone relates within an e...

Time To Escape the Comfort Zone Alrhough I have renewed my membership in rhe American Occuparional Therapy Associarion (AOTA) as a pracricing rherapisr, I am concerned abour our profession's furure. Wirh rhe influx of managed care dicraring healrh care delivery, occuparional rherapy is ar a crossroads berween sragnarion wirh professional parochialism and growrh wirh rhe vision of role enhanceme...

In this paper, we propose a successive interference cancellation (SIC) detector which utilises multiple feedback (MF) candidates for cancellation stages and a dynamic log-likelihoodratio (LLR)-based dynamic reliability ordering (RO) of the cancellation stages in a multiple-input multiple-output (MIMO) system. The proposed multi-feedback reliability-ordered SIC (MF-RO-SIC) detector’s performance...

Breast cancer cells express enzymes that convert cholesterol, the synthetic precursor of steroid hormones, into estrogens and androgens, which then drive breast cancer cell proliferation. In the present study, we sought to determine whether oxidosqualene cyclase (OSC), an enzyme in the cholesterol biosynthetic pathway, may be targeted to suppress progression of breast cancer cells. In previous ...

Rose-oxide is a fragrance found in roses and rose oil. There are no reports about the pharmacological activity of this molecule. The present study was undertaken to evaluate whether rose-oxide (RO) has anti-inflammatory properties and to investigate possible mechanisms involved with its effects. The anti-inflammatory activity of RO was first suggested by the formalin test in mice, an inflammato...