The Front Cover shows the Karlštejn Castle, a large Gothic castle founded in 1348 by Charles IV, Holy Roman Emperor-elect and King of Bohemia (and founder University Prague). served as place for safekeeping Imperial well Bohemian crown jewels, holy relics, other royal treasures. From synthetic chemist's point view, chiral ligands enabling high asymmetric inductions can be also considered jewels...

The design of reactive species that can either serve to initiate the ring-opening polymerization epoxides for synthesis high molar mass polyethers or be alternatively used catalyze polyether telechelics in presence chain transfer agents has long been an elusive goal. Here, we report a series bifunctional borinane-based catalysts enable living with unprecedented activity (TOF ? 1.8 × 105 h–1) an...

The uranyl aryloxide, [UO(2)(OAr)(2)(THF)(2)], and uranyl chloride, [UO(2)Cl(2)(THF)(3)] or [UO(2)Cl(2)(THF)(2)](2) act as pre-catalysts for the ring opening polymerization of propylene oxide and cyclohexene oxide. Coordination of the monomers has been investigated using (1)H EXSY spectroscopy and kinetic and thermodynamic parameters reported. NMR analyses of the polymers suggest a bimetallic m...

Selectivity rules in organic chemistry have been inferred largely from nonaqueous environments. In contrast, enzymes operate in water, and the chemical effect of the medium change remains only partially understood. Structural characterization of the "ladder" polyether marine natural products raised a puzzle that persisted for 20 years: Although the stereochemistry of adjacent tetrahydropyran (T...

Abstract Organic halide salts in combination with metal or organic compound are the most common and essential catalysts ring‐opening copolymerizations (ROCOP). However, role of was neglected. Here, we have uncovered complex behavior halides ROCOP epoxides aziridine cyclic anhydride. Coordination chain‐ends to cations, electron‐withdrawing effect, leaving ability atoms, chain‐end basicity/nucleo...

The reaction of different types of aromatic and aliphatic epoxides with sodium azide to give vicinal azido alcohols was studied in a microreactor with and without pillars in the channels. Dependent on the substrate, the regioselectivity of the ring opening is affected by the used solvent system, viz. acetonitrile–water (sometimes with 10% acetic acid to promote the reactivity of substrates) or ...