In nine conscious, chronically instrumented dogs, ultrasonic dimension transducers measured left ventricular anterior-posterior and septal-free wall minor axis and major axis diameters. Matched micromanometers measured right and left ventricular transmural and transeptal pressures. Ventricular pressures and volumes were varied by inflation of implanted vena caval and pulmonary artery occluders,...

OBJECTIVE The main purpose of present study was to investigate the impact of percutaneous closure of atrial septal defect (ASD) on right ventricular (RV) systolic function assessed by tricuspid annular isovolumic myocardial acceleration (IVA) that is independent of preload and afterload changes. METHODS A prospective cohort study was designed involving twenty five patients with secundum type ...

Pulsed Doppler echocardiograms were obtained from 42 normal fullterm neonates at less than 12 hours (20 subjects), 4 days (20 subjects), and 33 days (12 subjects). The acceleration time of the flow velocity and ventricular systolic time intervals were measured on recordings obtained at the right and left ventricular outflow tract, and the patency of the ductus arteriosus was evaluated by the fl...

BACKGROUND The right ventricle (RV) has an essential function in cardiovascular physiology and pathology. Currently, it is gaining an increasing interest given its recognized role in many cardiovascular conditions. However, echocardiographic assessment of the RV in daily practice is frequently based on qualitative estimation, and it has been regarded as a neglected chamber. OBJECTIVE We sough...

Background We have previously identified that right ventricular systolic dysfunction (RVSD), present in one third of patients with non-ischaemic dilated cardiomyopathy (DCM), is an independent predictor of all cause mortality and cardiac transplantation. CMR provides a robust and reliable way of quantifying RVSD. The natural history of RVSD in DCM has not been formally evaluated. We sought to e...

In the neonatal and pediatric intensive care setting, bedside cardiac ultrasound is often used to assess ventricular dimensions and function. Depending upon the underlying disease process, it is necessary to be able to evaluate the systolic and diastolic function of left and or right ventricles. The systolic function of left ventricle is mostly assessed qualitatively on visual inspection “eye-b...

The objectives of this study were to assess the feasibility of low flow right ventricular support and to describe the hemodynamic effects of low versus high flow support in an animal model of acute right ventricular pressure overload. A Synergy Pocket Micro-pump (HeartWare International, Framingham, MA) was implanted in seven sheep. Blood was withdrawn from the right atrium to the pulmonary art...

conclusions there is a significant increased incidence of mortality, prolonged hospitalization, and rehospitalization in symptomatic patients with severe tr. therefore, we recommend more aggressive approach toward tv repair or replacement in these patients regardless of pap and systolic function. results heart failure (50%) was the most cause of death. mean years of survival from diagnosis of s...

OBJECTIVE The purpose of this study was to quantify the magnitude of interaction between the right and left ventricles in conditions of heart failure. METHODS Human hearts were taken from transplant recipients diagnosed with diluted cardiomyopathy at the time of transplantation and were restored to beating condition with use of an isolated perfusion circuit. Left ventricular-right ventricular...

A 59-year-old white male with carcinoid tumor and hepatic metastases underwent hepatic artery embolization. The patient developed carcinoid crisis and a subsequent transthoracic echocardiogram showed classic findings of carcinoid heart disease along with a dilated hypertrophied right ventricle and severely depressed right ventricular ejection fraction. After treatment with octreotide the patien...