During ventilation, the lungs may serve as accessory pumps for forward blood flow. We have noted significant hemodynamic improvement in several patients during short periods of vigorous hand ventilation with the Ambu bag and tried to reproduce the hemodynamic improvement in the management of four patients with profound low cardiac output syndrome secondary to right ventricular (RV) failure foll...

abstract background: right ventricular myocardial performance index (rvmpi) is a doppler–derived parameter of non-geometrical ventricular function that measures both systolic and diastolic functions of the right ventricle. the aim of this study is to compare prognostic value of rvmpi with global rv function in patients undergoing coronary artery bypass graft (cabg). methods: in a longitudinal s...

The diagnostic ability of model-based monitoring systems offer significant clinical potential. This research tests, the clinical ability of a model-based system for tracking hemodynamic changes in a porcine study on septic shock and large pore hemofiltration (LPHF) therapy. Typically available or inferable intensive care unit (ICU) measurements are used to identify subject-specific models of th...

Background. The pericardium both limits cardiac distension and accentuates ventricular interdependence. Although this effect appears minimal under normal circumstances, the pericardium markedly restricts acute cardiac enlargement. Animal studies have demonstrated gradual pericardial adaptation and expansion in chronic volume overload and cardiomegaly, but the pericardial response in humans with...

BACKGROUND The pericardium both limits cardiac distension and accentuates ventricular interdependence. Although this effect appears minimal under normal circumstances, the pericardium markedly restricts acute cardiac enlargement. Animal studies have demonstrated gradual pericardial adaptation and expansion in chronic volume overload and cardiomegaly, but the pericardial response in humans with ...

The beneficial effects of cardiac resynchronization therapy (CRT) have been evaluated in several trials, and different degrees of response to CRT have been reported; indeed, the optimization of pacing sites and stimulation timing seems to be a major determinant of the hemodynamic response. For standard CRT delivery, the atrioventricular pacing interval is shortened to ensure consistent left ven...

The present study reports the development and characterization of a murine model of right ventricular dysfunction following graded constriction in the pulmonary artery via microsurgical approaches. To analyze in vivo ventricular function, a technique of x-ray contrast microangiography was developed to allow the quantitative analysis of ventricular volumes and of ejection fraction in normal and ...