BACKGROUND Rheumatoid arthritis has varied pleuroparenchymal manifestations. Wegener's granulomatosis can develop in an established case of rheumatoid arthritis and this association although previously reported is very rare. CASE PRESENTATION A 60-year-old lady had been diagnosed with rheumatoid arthritis on the basis of her clinical symptoms and serological tests which were positive RA facto...

The characteristic cutaneous rheumatoid nodule, described fully by Collins (1937) and Bennett, Zeller, and Bauer (1940), is composed of a central area of fibrinoid necrosis around which develops an encircling corona of closely packed mesenchymal cells, the great majority of which appear to be fibroblasts (Collins, 1937), and external to this is a zone of inflammatory tissue. Lesions with simila...

The incidence and structure of subcutaneous nodules in rheumatic fever and rheumatoid arthritis have been the subject of research for many years. In 1937 Collins published a paper on the subcutaneous nodule in rheumatoid arthritis, and in 1939 he reviewed in these Annals some of the work on the pathology of rheumatic fever and rheumatoid arthritis. He mentions the basic pattern of tissue change...

the nodular thyroid diseas is one of the most common disturbances o the thyroid gland wheras malignant tumors are among the most unusual entities of it. not only differentiation of these two spectra but also the problems to achieve early diagnosis and treatment, have been a matter of concern, research, and controversy. two hundred patients were assessed at the cancer institute of imam khomeini ...

Tularemia is a zoonotic disease caused by Francisella tularensis that can be transmitted to humans when they handle rabbits, receive tick bites, consume contaminated water, or inhale aerosolized particles. We present the case of a 51-year-old white man with rheumatoid arthritis who was taking immunosuppressive medications and presented with tularemia. Our patient acquired the typhoidal form of ...

Background Pulmonary rheumatoid nodule(RPN) is an serious extraarticular manifestation of arthritis (RA). The clinical features and activity the RA, used DMARDs characteristics nodule may affect progression RPN. [1] Objectives To identify PRN factors affecting its progression. Methods In this study, 4117 patients with RA according to ICD-10 code from hospital database who had at least one compu...

OBJECTIVE In view of the possible role of androgens in the pathogenesis of rheumatoid arthritis (RA), this study investigated the association between repeat lengths of CAG microsatellites of the androgen receptor (AR) gene and RA. METHODS The number of CAG repeats in exon 1 of the AR gene was determined in 90 men and 276 women with RA, as well as in 305 male and 332 female controls. RESULTS...

The latex-fixation test (Singer and Plotz, 1956) is widely used as a serological criterion for rheumatoid arthritis (Alexander and McCarthy, 1966; Walton, 1968). The test is often carried out in serial dilution, by which a titre as well as an agglutination pattern is obtained. The usual practice is to choose a borderline titre in an empirical way and to call all titres above the borderline valu...