40years female presented with vaginal wall polyp for 6months underwent polypectomy. Grossly, received single grey white soft tissue mass measuring 2cm in diameter. Formalin fixed paraffin embedded tissue sections were made and subjected to Haematoxylin and Eosin staining. H&E section studied on low power view showed well circumscribed mass within the submucosa having irregular borders with brig...

BACKGROUND Neonatal Tuberose sclerosis complex may be associated with symptomatic cardiac rhabdomyomas. Cardiac rhabdomyomas are the most common cardiac tumours. The symptoms include haemodynamic instability and life threatening arrhythmias usually requiring early surgical intervention. RESULTS We report a case of a 32 week gestation newborn diagnosed with a right ventricular outflow tract ma...

Fig. S2. Results of analysis for the PTCH1 mutation identified in the patient. DNA sequencing analysis showing the splice site mutation c.585-1G>A (denoted with arrow) in heterozygosis (A). RT-PCR analysis (B). A cDNA fragment (431 bp) was amplified with the forward primer Ex2cF:5’TAAAAGCAGCGAACCTCGAG-3’ and the reverse Ex6cR:5’-AAGTTTGTCCACCGCAAAGGA-3’ encompassing part of exon 2 (49 bp), exon...

Results Fetal abnormalities were observed in 45 (3. 7 %) of the cases. We were able to diagnose all the cases of hydrocephalus and ventriculomegaly, cranial menigocele, spina bifida, cleft lip and palate, micrognathia, cyst of lacrimal duct, hydronephrosis, renal agenesis simple renal cyst, clubhands, talipes, polydactyly, rib agenesis, diaphragmatic hernia, CCAM, atrial and atrioventricular se...

Rhabdomyomas are the most common cardiac tumors in infancy and childhood. Surgery is reserved for those patients with hemodynamic compromise. We present a case of surgical resection of a large mass obstructing the left ventricular outflow tract in a neonate.

A14-year-old girl with a history of a congenital cardiac tumor presented to our echocardiography laboratory for a routine reexamination. The diagnosis had been made in our laboratory in 1991 on her seventh day of life using an old-generation ultrasound machine (SSH-40A, Toshiba Medical Systems, Tokyo, Japan). The newborn had undergone echocardiographic evaluation because of a systolic murmur. D...