OBJECTIVES To analyse the changes of ocular haemodynamics and morphology in Chinese patients with internal carotid artery (ICA) stenosis in the current study. METHODS A retrospective case-control study was conducted with 219 patients. The haemodynamic characteristics, the calibre of retinal vessels, and the subfoveal choroidal thickness (SFChT) were compared. We analysed the correlations with...

BACKGROUND AND OBJECTIVE Birdshot chorioretinitis is a rare disease independently involving the retina and the choroid. Retinal involvement has deleterious functional consequences. This study aimed to follow retinal profiles in early (< 1 year, untreated), intermediate (1 to 6 years, receiving therapy), and late (> 6 years) birdshot chorioretinitis. PATIENTS AND METHODS Optical coherence tomo...

PURPOSE We aimed to visualize the retinal arterial wall thickness, assisted by noninvasive adaptive optics scanning laser ophthalmoscopy (AO-SLO). METHODS The arterial wall thickness was measured and compared between one normal subject and one patient suffering from malignant hypertensive retinopathy. RESULTS Increased arterial wall thickness was revealed with a newly developed AO-SLO syste...

Purpose Prospective treatments for age-related macular degeneration and inherited retinal degenerations are commonly evaluated in the Royal College of Surgeons (RCS) rat before translation into clinical application. Historically, retinal thickness obtained through postmortem anatomic assessments has been a key outcome measure; however, utility of this measurement is limited because it precludes...

PURPOSE To evaluate the thickness of the 10 retinal layers in the paramacular area of Parkinson disease patients using a new segmentation technology of optical coherence tomography (OCT) to examine whether the thickness of specific layers predicts neurodegeneration or Parkinson disease severity. DESIGN Observational prospective study. METHODS Parkinson disease patients (n = 129) and age-mat...

PURPOSE Morphologic changes in the retina and choroid are closely related with high myopia-related diseases. This study was conducted to evaluate the morphologic characteristics of normal highly myopic eyes. METHODS Thirty-one phakic highly myopic eyes with no posterior abnormalities (18 patients; mean +/- SD age, 51.7 +/- 11.4 years) were enrolled. Retinal-choroidal thickness at the fovea 1....

OBJECTIVE To examine the 1-year alterations of the blood-retinal barrier and changes in retinal thickness occurring in the macular region in patients with type 2 diabetes mellitus and mild nonproliferative retinopathy. METHODS We classified 12 eyes of 12 patients with type 2 diabetes mellitus and mild nonproliferative retinopathy by 7-field stereoscopic fundus photography, levels 20 and 35 of...

AIMS To compare histological thickness of the retinal nerve fibre layer in the primate with retardation measurements obtained in vivo using the Mark II Nerve Fiber Analyzer (NFA, Laser Diagnostic Technologies, San Diego, USA). METHODS Scanning laser polarimetry was performed on both eyes of a healthy anaesthetised adult primate (Macaca mulatta). The retinal nerve fibre layer thickness was mea...

Purpose To analyze retinal thickness (RT) and choroidal thickness (ChT) changes in patients with unilateral nongranulomatous acute anterior uveitis (AAU) using three-dimensional (3D) 1060-nm optical coherence tomography (OCT). Methods Retinal and choroidal thickness maps were statistically analyzed for 24 patients with newly diagnosed unilateral AAU before therapy. A total of 17 patients were...