Trypsin digestion of retinal pigment epithelium is a technique that bares Bruch's membrane, to allow topographical examination by scanning electron microscopy. Twenty-five human eyes were examined. The zonula occludens of the pigment epithelium was clearly seen as a surface feature, but attachment plaques at the sides and base were not visible. The adhesion between the pigment epithelium and th...

The cytochemical localization of G6Pase activity, which is specific to the endoplasmic reticulum (ER) of Müller cells, was studied after argon laser photocoagulation in the guinea pig retina. After argon laser radiation, Müller cells exhibited enlargement of the cytoplasm, an increase of reactive ER and the nuclei, dislocation of the nuclei and diagonal stretching of the cytoplasm. However, cel...

PURPOSE Adhesion and migration of dislocated retinal pigment epithelial (RPE) cells are initial steps in the pathogenesis of proliferative vitreoretinopathy (PVR). The role of the endogenous lectin, galectin-1, in attachment, spreading, and migration of human RPE cells was investigated from a therapeutic perspective. METHODS Human RPE cells were treated with galectin-1 concentrations that ran...

British Journal of General Practice, October 2012 557 INTRODUCTION Medical school does little to prepare future GPs for the relatively large number of patients with ophthalmic complaints they will see in everyday practice, so spending a 4-month attachment in ophthalmology is a good way to fill in any gaps in your knowledge. The beauty of ophthalmology is that it bridges medicine and (micro)surg...

Typically developing adults and children can rapidly reach consensus regarding the trustworthiness of unfamiliar faces. Maltreated children can have problems with trusting others, yet those with the disinhibited form of reactive attachment disorder (dRAD) can be indiscriminately friendly. Whether children with dRAD symptoms appraise and conform to typical judgements about trustworthiness of fac...

purpose : to evaluate the structural outcomes of treated neonates with retinopathy of prematurity (rop) methods : in this cross-sectional study from april 2008 to august 2009, 859 patients were investigated. these neonates had been consulted at the retinal clinic of farabi eye hospital of tehran university of medical sciences. those with gestational age of no more than 36 weeks and birth weight...

background and purpose: occular toxicity is one of the most important complications of hydroxychloroquine. not any type of treatment has so far been found and recommended for this disorder. the purpose of this study was to report some characteristics of patients with hydroxychloroquine induced retinopathy.    materials and methods: from 107 patients with rheumatoid arthritis (ra) and/or systemi...