DESCRIPTION A 45-year-old woman was admitted for a painful purpuric rash on her cheeks, ears and legs, which began after a 3-day period of heavy crack cocaine use. She reported a similar rash 3 years ago and a skin biopsy at that time revealed thrombi in the small blood vessels. However, serological testing was not consistent with any specific known diagnosis and she was discharged when her ras...

Cocaine-induced vasculitis is a rare complication found in drug abusers. It occurs due to cocaine adulterated with levamisole. Levamisole was once used as a chemotherapy and immunomodulator for different conditions. One of the side effects of this medication is necrotizing vasculitis which has been reported in the US and Puerto Rico. Here we present another case of cocaine induced vasculitis in...

To cite: Yek C, Li X, Mauskar M. BMJ Case Rep Published online: [please include Day Month Year] doi:10.1136/bcr-2016219077 DESCRIPTION A 56-year-old man presented with a 2-day history of a painful rash. Examination revealed necrotic retiform purpura over the trunk and extremities (figure 1). Laboratory testing was notable for leucopenia (3.2 cells/mL) and positive peripheral antineutrophil cyto...

The documented data regarding the three-dimensional structure of the air capillaries (ACs), the ultimate sites of gas exchange in the avian lung is contradictory. Further, the mode of gas exchange, described as cross-current has not been clearly elucidated. We studied the temporal and spatial arrangement of the terminal air conduits of the chicken lung and their relationship with the blood capi...

Endometrial stromal tumors are reviewed with emphasis on their wide morphologic spectrum and problems in differential diagnosis, highlighting issues that have received particular attention in the recent literature. These neoplasms are divided into two major categories--endometrial stromal nodules and endometrial stromal sarcomas--a distinction made on the basis of the lack of significant infilt...

Local complications associated with glatiramer acetate are frequent, especially at the injection site. The presence of pain, oedema, and local erythema is almost a given in areas where the drug is administered subcutaneously. However, the presence of cutaneous necrosis should alert doctors to the possibility of impairment of underlying vascular structures. Nicolau syndrome or embolia cutis medi...

MALABSORPTION syndromes are clinical disorders arising from disturbances of small intestinal function although pernicious anaemia is not usually included in this category. The principal disorders are coeliac disease, post-gastrectomy states and small intestinal diverticulosis. Tropical sprue and regional enteritis both with a high incidence of low levels of serum vitamin B12 are also included a...

Keratosis lichenoides chronica or nekam disease is a rare dermatosis of unknown etiology. It is characterized by linear and reticulate lesions of lichenoid appearance, scaly plaques, and keratotic papules on the trunk and limbs. In addition to these 3 characteristic features, there may also be an eruption on seborrheic areas of the face. This clinical variability, the numerous confusing names g...

Keratosis lichenoides chronica or nekam disease is a rare dermatosis of unknown etiology. It is characterized by linear and reticulate lesions of lichenoid appearance, scaly plaques, and keratotic papules on the trunk and limbs. In addition to these 3 characteristic features, there may also be an eruption on seborrheic areas of the face. This clinical variability, the numerous confusing names g...