Background: Lithium is a therapeutic option for the treatment of the acute phase of the bipolar disorder and long-term management of this disorder. However,  it  is  estimated  that  10  to  60%  of  patients  do  not  properly response to this medication. Methods: To investigate the role of MARK2 gene in response to lithium, we genotyped the MARK2 rs10792421 polymorphism in Iranian bipolar pa...

Background and aim: Pentavalent antimony compounds are the first line treatment for cutaneous leishmaniasis. Clinical resistance to pentavalent antimony in the form of meglumine antimoniate (Glucantime) has been recognized as a problem in leishmaniasis. Herein, clinical response to Glucantime were studied in patients suffered from cutaneous leishmaniasis.Materials and Methods: In a cross-sectio...

Results: Response of skin warty lesions to treatment with intralesional 5-FU was as following: complete response was seen in 200 (80.0 %), partial response was seen in 37 (14.8 %) of cases and no response was recorded in 13 (5.2 %) of cases. There was no significant association between size of warty lesion and response to intralesional 5-FU (p = 0.154), but there was significant association bet...

Background: Topical immunotherapy with diphencyprone (DPCP) for the treatment of severe alopecia areata has been used since 1983 and is felt to be the treatment of choice for chronic extensive alopecia areata. Highly variable results have been reported. The purposes of this study were to evaluate the efficacy of DPCP in the treatment of chronic, extensive alopecia areata and to assess the...

conclusions: absence of the c allele was significantly associated with failure of response. the presence of c allele was associated with a favorable outcome. afp is a strong baseline predictor of hcv treatment response. a decision tree model is useful for predicting the probability of response to therapy. patients and methods: the study included 263 chronic hcv egyptian patients receiving peg-i...

Collagenous colitis: response to treatment Sir, Rokkas et al.1 report an interesting case of collagenous colitis showing a rapid clinical response to sulphasalazine therapy with apparent complete resolution of the collagen band. It is now becoming clear that a significant proportion of cases of collagenous colitis do respond to anti-inflammatory therapy of the type effective in idiopathic infla...

we report a case of prostatic adenocarcinoma, initially presenting with generalized lymphadenopathy, and mimicking lymphoma on flurodeoxyglucose positron emission tomography/computed tomography (fdg pet/ct). our case suggests that in elderly men presenting with generalized lymphadenopathy, the diagnosis of metastatic prostatic carcinoma should not be overlooked even in the absence of typical ur...