Coronavirus disease (COVID-19) is a contagious respiratory that causing significant global morbidity and mortality. Understanding the impact of Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) infection on host metabolism still in its infancy but great importance. Herein, we investigated metabolic response during viral shedding post-shedding an asymptomatic SARS-CoV-2 ferret model (...

Diatoms are microalgae well known for their high variability and primary productivity, being responsible about 20% of the annual global carbon fixation. Moreover, they interesting as potential feedstocks production biofuels high-value lipids carotenoids. exhibit trophic flexibility and, under certain conditions, can grow mixotrophically by combing photosynthesis respiration. So far, only a few ...

A large literature exists on the metabolism of spontaneous and transmissible tumors. At least one host factor complicates all of these studies, namely the mixture of host tissues with the tumor. Only microscopic portions of tumors growing in animals are free of connective tissue, wandering cells, or blood vessels contributed by the host. Any measurement of the metabolism of a tumor derived dire...

The inhibitor of mitochondrial pyruvate transport alpha-cyano-beta-(1-phenylindol-3-yl)-acrylate was used to inhibit progressively pyruvate carboxylation by liver mitochondria from control and glucagon-treated rats. The data showed that, contrary to our previous conclusions [Halestrap (1978) Biochem. J. 172, 389-398], pyruvate transport could not regulate metabolism under these conditions. This...

Cyanobacteria combine the photosynthetic and respiratory electron transport in one membrane system, the thylakoid membrane. This feature requires an elaborate regulation mechanism to maintain a certain redox status of the electron transport chain, hence allowing proper photosynthetic and respiratory energy metabolism. In this context, metabolic adaptations, as seen in the light-todark and dark-...

Overview 39 Gestational Weight Gain 39 Cardiovascular System 39 Heart 39 Cardiac Output 39 Arterial Blood Pressure and Systemic Vascular Resistance 41 Venous Pressure 41 Central Hemodynamic Assessment 41 Normal Changes That Mimic Heart Disease 42 Effect of Labor and the Immediate Puerperium 42 Cardiac Rhythm 43 Hematologic Changes 43 Plasma Volume and Red Cell Mass 43 Iron Metabolism 44 Platele...

Aerobic enhanced glycolysis characterizes the Warburg phenotype. In cancer cells, suppression of mitochondrial metabolism contributes to maintain a low ATP/ADP ratio that favors glycolysis. We propose that the voltage-dependent anion channel (VDAC) located in the mitochondrial outer membrane is a metabolic link between glycolysis and oxidative phosphorylation in the Warburg phenotype. Most meta...

PURPOSE Many solid tumors exhibit abnormal aerobic metabolism characterized by increased glycolytic capacity and decreased cellular respiration. Recently, mutations in the nuclear encoded mitochondrial enzymes fumarate hydratase and succinate dehydrogenase have been identified in certain tumor types, thus demonstrating a direct link between mitochondrial energy metabolism and tumorigenesis. Alt...

the recently emerged middle east respiratory syndrome coronavirus (mers-cov) emerged in the middle east region in 2012. the virus is phylogenetically related to bat cov, but other animal species like camels and goats may potentially act as an intermediate host by spreading the virus to humans. this virus is thought to cause a severe disease in patients with underlying comorbidities. laboratory ...

respiratory syncytial virus (rsv) is the major cause of lower respiratory tract infections in infants,and also an important factor for hospitalization during the winter months. to determine the prevalence and importance of rsv as a cause of acute lower respiratory tract infection, we carried out a prospective study during 5 months period from november to march 1998 in 6 pediatric hospitals. a n...