We studied the effects of administering exogenous surfactant for the treatment of respiratory distress in premature neonates (born before 37 weeks of gestational age [GA]) and compared the role of different risk factors on the outcome as well as survival rate. All the neonates (242) suffered from moderate to severe respiratory distress, identified by clinical signs, chest X-ray, respiratory dis...

introduction respiratory distress syndrome (rds) is a current cause of morbidity in premature infants resulted from surfactant deficiency. the primary aim of this randomized study was to describe the feasibility of early administration of surfactant via a thin catheter during spontaneous breathing (tec) and compare its outcomes with the insure (intubate, surfactant, extubate) procedure material...

Surfactant deficiency and the resultant respiratory distress syndrome (RDS) seen in preterm infants is a major cause of respiratory morbidity in this population. Until recently, the contribution of surfactant to respiratory morbidity in infancy was limited to the neonatal period. It is now recognised that inborn errors of surfactant metabolism leading to surfactant dysfunction account for aroun...

In preterm infants, RDS is primarily caused by deficiency of pulmonary surfactant in an immature lung. For the past 50 years, related research and experiments with regards to surfactant replacement therapy have been encouraging and inspiring. Numerous trials have been conducted to demonstrate that surfactant plays an important role in the management of respiratory distress syndrome in preterm b...

OBJECTIVE To examine the effect of hypertensive disease of pregnancy (HDP) on the development of respiratory distress syndrome (RDS) in preterm neonates. DESIGN A retrospective cohort study. SETTING All neonatal intensive care units in New South Wales and the Australian Capital Territory. PATIENTS A total of 18,845 preterm neonates aged between 24 and 36 weeks gestation admitted to the un...

Respiratory distress presents as tachypnea, nasal flaring, retractions, and grunting and may progress to respiratory failure if not readily recognized and managed. Causes of respiratory distress vary and may not lie within the lung. A thorough history, physical examination, and radiographic and laboratory findings will aid in the differential diagnosis. Common causes include transient tachypnea...

Although the respiratory distress syndrome (RDS) has been the subject of extensive study and review, the clinical and prognostic evaluation, and the therapy, still present considerable difficulties. This report concerns a progressive change in the electrocardiogram, which was found to be of value in assessing severity and prognosis. Attention was drawn to these variations in pattern in a recent...

The efficacy of surfactant preparations used in the prevention and treatment of respiratory distress syndrome (RDS) is a well known fact; however, many controversies remain. The debate over which surfactant to be used, when and what is the best mode of delivery is still raging. Currently, animal-derived surfactants are preferred and clearly recommended by various practice guidelines, but new sy...

The major causes of pulmonary hypertension (PH) in children are congenital heart defect (CHD) and PH associated with prematurity, respiratory distress syndrome (RDS) and bronchopulmonary dysplasia (BPD). Idiopathic pulmonary arterial hypertension (PAH) and PAH associated with genetic mutations are also known to manifest in the pediatric age group. This review will mainly discuss the problems en...

Objective: To determine the outcome of preterm neonates with early introduction bubble continuous positive airway pressure (CPAP). Methodology: This observational study was conducted in NICU Shifa International Hospital, Islamabad from March 2017 to August 2017. Ninety infants were enrolled a gestational age 28 37 weeks and clinical features Respiratory Distress Syndrome (RDS). Infant variables...