Background: During the last decade, enterococci have become important nosocomial pathogens, representing the second leading cause of urinary tract infections. This increasing prevalence has been paralleled by the occurrence of multi-drug resistant (MDR) and high-level gentamicin resistant (HLGR) strains. Methods: From September 2005 to 2006, a total of 638 enterococcal isolates were collected ...

Aims and Background: E. coli is a normal flora of the human and animal intestine that sometimes causes pathogenesis in the intestine and urinary tract. The aim of this study is to investigate resistance genes in E. coli isolated from toilets in the Islamic Azad University of Mashhad and perform genome sequencing in tetracycline-resistant strains. Methods: This cross-sectional study was perform...

Abstract This study aimed to detect carbapenemase genes and determine the in vitro susceptibility of Ceftazidime-Avibactam (CZA) Enterobacterales isolates. Carbapenemase were detected by polymerase chain reaction. CZA sensitivity isolates was evaluated with broth microdilution (BMD) disk diffusion methods. A total 318 carbapenem-resistant included. Most ( n = 290, 91.2%) identified as Klebsiell...

acquired azole resistance in opportunistic fungi causes severe clinical problems in immunosuppressed individuals. this study investigated the molecular mechanisms of azole resistance in clinical isolates of candida glabrata . six unmatched strains were obtained from an epidemiological survey of candidiasis in immunocompromised hosts that included azole and amphotericin b susceptible and azole r...

conclusions the results indicate that multidrug-resistant (mdr) strains of salmonella are increasing in number, and fewer antibiotics may be useful for treating s. enterica infections. routine investigation and reporting of antibiotic mics in patients presenting with salmonella infections is suggested. results of the total 19 salmonella spp. isolates recovered by the bactec automated system, al...

background and objectives: macrolide, lincosamide and streptogramin b (mlsb) antimicrobial agents are widely used in the treatment of staphylococcal infection. clindamycin is the medicine of choice for some staphylococcal infections, particularly skin and soft tissues infections. erythromycin and clindamycin are two distinct classes of antimicrobial agents which inhibit protein synthesis in bac...

Mupirocin resistance was determined in consecutive oxacillin-resistant and borderline oxacillin-resistant Staphylococcus aureus clinical isolates collected over 14 months at a university hospital during 1991 and 1992. Twenty of 86 (23%) oxacillin-resistant and borderline oxacillin-resistant S. aureus isolates were mupirocin resistant; 80% were high-level resistant. Prior mupirocin use was a sig...

background: the emergence and propagation of different phylogenetic groups of antimicrobial-resistant e. coli have become a worldwide health concern in human and veterinary medicine. therefore, the evaluation of the phylogenetic distribution of antibiotic-resistant e. coli is important for therapeutic and economic purposes. the aims of this study were to determine phylogenetic groups and patter...

conclusions more than behalf of the wound isolates were esbl positive, and the presence of blaveb-1 was determined in less than half of these isolates. fortunately, resistance to imipenem and meropenem was low. results the majority of the wound isolates were resistant to augmentin (90%, n = 80) and cefpodoxime (87.6%, n = 78). however, the majority was susceptible to imipenem and meropenem. fif...

Background: Multidrug-resistant efflux pumps are one of the most significant methods by which bacteria can evade effects numerous antimicrobials. The aim this study was to determine prevalence multidrug-resistant MDR, extremely drug-resistant XDR, and pan-drug-resistant PDR K. pneumoniae phenotypes in clinical isolates, as well examine detection pump genes ompK35, ompK36, tolC, acrAB strains.&#...