The efficacy and safety of the new oral anticoagulants (NOAC) and the benefits of extended duration thromboprophylaxis following hip and knee replacements remain uncertain. This observational study describes the relations between thromboprophylaxis policies following hip and knee replacements across England's NHS and patient outcomes between January 2008 and December 2011. From the national adm...

Introduction With the globally increasing life expectancy and improved outcome of congenital heart disease, the number of cardiac device implantations is increasing steadily. A prolonged pacemaker (PM) therapy period is associated with potential long-term complications. Thereby battery and electrode longevity have not improved in the past decades, leading to recurrent device and electrode repla...

In this study we report the results of thumb carpometacarpal (CMC) joint replacements in the Norwegian population over a 17-year period. In total, 479 primary replacements performed from 1994 to 2011 were identified in the Norwegian Arthroplasty Register. Implant survival and risk of revision were analyzed using Cox regression analyses. Four different implant designs were compared and time tren...

Meal replacements are a safe and effective tool for weight loss and weight management and beyond. Recent research and concepts suggest that the category can provide additional metabolic and nutritional benefits not previously recognized. Recent studies indicate that use of protein‐enriched meal replacements helps maintain lean body mass during weight loss, providing additional metabolic benefit...

A computer-aided analysis has been carried out on 176 knee replacements performed on 129 patients during the last 12 years. Owing to the variety of knee replacements used, the number of complications seen, and the large quantity of survey data a computer was very helpful in storing this amount of data with facilities for rapid recall of information. The results of the early Shiers knee hinged a...

The amino acid sequences of the eye lens protein alpha-crystallin A from many mammalian and avian species, two frog species, and a dogfish have provided detailed information about the molecular evolution of this protein and allowed some useful inferences about phylogenetic relationships among these species. We now have isolated and sequenced the alpha-crystallins of the American alligator and t...

Despite having been quite popular during the 1990s because of their important advantages, linked cache coherence protocols have gone completely unnoticed in the multicore wave. In this work we bring them in the spotlight, demonstrating that they are a good alternative to other solutions being proposed nowadays. In particular, we consider in this work the case for a simply-linked list-based cach...