Inflammatory bowel disease is associated with an increased risk of mental disorders and can be exacerbated by stress. In this study which was performed with male 10-week old C57Bl/6N mice, we used dextran sulfate sodium (DSS)-induced colitis to evaluate behavioral changes caused by intestinal inflammation, to assess the interaction between repeated psychological stress (water avoidance stress, ...

Repeated exposure to social stress can precipitate the development of psychosocial disorders including depression and comorbid cardiovascular disease. While a major component of social stress often encompasses physical interactions, purely psychological stressors (i.e. witnessing a traumatic event) also fall under the scope of social stress. The current study determined whether the acute stress...

Stress is a daily phenomenon faced by every living being and it is essential for learning. The body response to stress involves a fight and flight response in which biological changes, prepares the body for emergency action. The aim of the present study is to find out the fifteen days repeated noise, stress exposure induced alterations in the carbohydrate metabolism and its prevention by treatm...

Background: The functions of the monoamine neurotransmitters dopamine (DA) and serotonin (5-HT) in the etiology and treatment of depressive disorders are currently an area of intense research. Much of this research has focused on a relevant animal model of depression as a means of understanding the biological mechanisms underlying human anxiety and depression. Our studies examine whether change...

Underwater sound generated by pile driving during construction of offshore wind farms is a major concern in many countries. This paper reports on the acoustic stress responses in young European sea bass Dicentrarchus labrax (68 and 115 days old), based on four in situ experiments as close as 45 m from a pile driving activity. As a primary stress response, whole-body cortisol seemed to be too se...

BACKGROUND Stress fractures are the injuries of soft tissues and bones caused by intensive and repeated stress on a bone. Repeated submaximal stress disturbs the balance between the processes of bone production and resorption that results in fracture. CASE REPORT We presented a case of a patient with stress fracture of metatarsal bone. The patient was diagnosed and treated as having reactive ...

An impact fatigue study has been made for the first time on 63⋅5% glass fibre reinforced vinylester resin notched composites. The study was conducted in a pendulum type repeated impact apparatus especially designed and fabricated for determining single and repeated impact strengths. A well-defined impact fatigue (S–N) behaviour, having a progressive endurance below the threshold single cycle im...

The hippocampus is vulnerable to the damaging actions of insults such as transient ischemia and repetitive stimulation, as well as repeated exposure to exogenous glucocorticoids. This study investigated effects of a repeated psychological stressor, restraint, on the CA3 pyramidal neurons which are vulnerable to damage by repetitive stimulation. Repeated daily restraint stress for 21 days caused...

There is a cost of stress that may result in the loss of normal biological function (e.g., growth). Repeated, and even single, applications of stressors have been shown to induce negative energy balance in rodents. However, here we addressed whether this energetic response changes during multiple stress exposure and whether there is complete recovery subsequent to the cessation of stress exposu...

The precise mechanisms by which beneficial responses to acute stress are transformed into long-term pathological effects of chronic stress are largely unknown. Western blot analyses revealed that members of the AP1 transcription factor family are differentially regulated by single and repeated stress in the rat adrenal medulla, suggesting distinct roles in establishing stress-induced patterns o...