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aim : in this study, genetic polymorphism of two trna-liked short tandem repeat (str)-containing loci, r-r and s-q, was analyzed in order to clarify further the genotypic differences among e. dispar isolates. background : entamoeba dispar is closely related to the human pathogen e. histolytica , the agent of amebic dysentery and amebic liver abscesses. e. dispar is, to some extent, capable of p...
OBJECTIVES Among persons in current HIV outpatient care, data on opioid prescribing are lacking. This study aims to evaluate predictors of repeat opioid prescribing and to characterize outpatient opioid prescribing practices. METHODS Retrospective cross-sectional study of persons ≥18 years in HIV outpatient care who completed an annual behavioral assessment between June 2008 and June 2009. Pe...
introduction: polymorphism in genes involved in folate metabolism may cotribute to the susceptibility to acute lymphoblastic leukemia (all). patients and methods : to examine the influence of polymorphism in thymidylate synthase (ts 28-bp repeat) and methionine synthase (ms a2756g) genes on the susceptibility to all, 73 children with all and 128 age and gender matched, unrelated healthy individ...
BACKGROUND Idiopathic and diabetic gastroparesis in Homo sapiens cause significant morbidity. Etiology or risk factors have not been clearly identified. Failure to sustain elevated heme oxygenase-1 (HO1) expression is associated with delayed gastric emptying in diabetic mice and polymorphisms in the HO1 gene (HMOX1, NCBI Gene ID:3162) are associated with worse outcomes in other diseases. AIM ...
The evolution of larger mammals resulted in a corresponding increase in peripheral nerve length. To ensure optimal nervous system functionality and survival, nerve conduction velocities were likely to have increased to maintain the rate of signal propagation. Increases of conduction velocities may have required alterations in one of the two predominant properties that affect the speed of neuron...
A truncated form of the Huntington's disease (HD) protein that contains the polyglutamine repeat, Httex1p, causes HD-like phenotypes in multiple model organisms. Molecular signatures of pathogenesis appear to involve distinct domains within this polypeptide. We studied the contribution of each domain, singly or in combination, to sub-cellular localization, aggregation and intracellular Ca2+ ([C...
In this research seismicity parameters, repeat times and occurrence probability of large earthquakes are estimated for 35 seismic lineaments in Persian plateau and the surrounding area. 628 earthquakes of historical time and present century with MW>5.5 were used for further data analysis. A probabilistic model is used for forecasting future large earthquake occurrences in each chosen lineament....
In the present study, genetic diversity among 41 lines and genotypes of canola including 19 open-pollinated and hybrid cultivars, 17 promising lines and 5 double-haploid lines were determined using simple sequence repeat (SSR) markers related on drought tolerance QTLs. Thirty-six selected primers produced 166 discernible bands, with 157 (94.58%) being polymorphic, indicating considerable geneti...
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