نتایج جستجو برای: release floating tablet

تعداد نتایج: 262841  

2011
A. Kotwal

Intragastric buoyant tablets, i.e., gastro retentive drug delivery systems of Amoxycillin trihydrate were prepared with the objective to obtain site-specific drug delivery for the stomach and to extend its duration of action. The sustained release of amoxicillin is desired because of its short biological half-life. Part icularly to treat Helicobacter pylori infections, the sustained release is ...

Journal: :Chemical & pharmaceutical bulletin 2008
Hiroyuki Maeda Yutaka Ogawa Masato Ishiyama Tomoaki Hirayama Katsuhide Terada

The purpose of this study was to obtain a nicorandil pulsatile release tablet that has a well-regulated release lag time. When nicorandil is used as an antiangina drug, administration time control is important. A pulsatile release tablet is one of the effective approaches to modified release to reduce daily administration frequency. In this study, a pulsatile release tablet of nicorandil was fo...

2014
Mahmood Ameen Abdulla Ibrahim Banat Patrick Naughton

During the past two decades, the identification of new scientific developments to improve outcomes in gastrointestinal disorders has been attractive to many researchers. Pharmaceutical industries are now more motivated to introduce novel therapeutic remedies in the treatment of gastrointestinal disorders. Such disorders have increased at an exponential rate in various patient communities and bo...

Journal: :iranian journal of pharmaceutical research 0
hr patel mm patel

the aim of the present study was to prepare and evaluate an osmotically controlled mucoadhesive cup-core (ocmc) containing aceclofenac. a special technique was used while preparing an ocmc. stability of ocmc was determined in natural human saliva, and it was found that both ph and device are stable in human saliva. ocmc was evaluated by weight uniformity, thickness, hardness, friability, swelli...

2016
Jin Li Hongyu Chai Yang Li Xuyu Chai Yan Zhao Yunfan Zhao Tao Tao Xiaoqiang Xiang

BACKGROUND Amoxicillin is a commonly used antibiotic which has a short half-life in human. The frequent administration of amoxicillin is often required to keep the plasma drug level in an effective range. The short dosing interval of amoxicillin could also cause some side effects and drug resistance, and impair its therapeutic efficacy and patients' compliance. Therefore, a three-pulse release ...

Journal: :Journal of Drug Delivery and Therapeutics 2021

Hypertension, or high blood pressure, is a major public health concern around the world because of its large contribution to global burden and function as risk factor for variety disease processes. Bosentan SR Floating Bilayer Tablets were made with HPMC K4M, E-15, E-15 alone (80%) in combination varying percentages polymer (20&60 percent, 40&40 60&20 percent ). The hydrophilic used...

Journal: :Jurnal ilmiah farmasi Akademi Farmasi Jember 2023

Furosemide is a sulfonamide-derived diuretic drug which an alternative treatment for heart failure. was made into slow-release tablets to improve the criteria poor furosemide and maximize its absorption in stomach. The purpose of this study determine whether floating with concentration 23% carbopol matrix could meet requirements evaluating physical properties compared theoretically literatur. r...

Journal: :iranian journal of pharmaceutical sciences 0
umme hani phd research scholar shivakumar h.g. department of pharmaceutics, jss college of pharmacy, jss university, sri shivarathreeshwara nagar, mysore-570 015, karnataka, india. gowrav mp department of pharmaceutics, jss college of pharmacy, jss university, sri shivarathreeshwara nagar, mysore-570 015, karnataka, india.

hydrogel based metronidazole bioadhesive tablet (hmbt) was prepared as a novel vaginal delivery system to achieve controlled release of drug from the tablet for vaginal candidiasis. the highly swollen hydrogel were prepared by dissolving chitosan in acetic acid solution containing drug, followed by neutralisation with sodium hydroxide and characterized by sem, dsc and ft-ir and evaluated for % ...

2015
Rahul kumar Garg Indrajeet Singhvi

Novel drug delivery system overcomes the physiological problems of gastric retention by decreasing fluctuations in blood drug concentration with consequent reduction in undesirable toxicity and poor efficiency. Incorporation of drug in controlled release gastroretentive dosage forms which can remain in the gastric region for several hours would significantly prolong the gastric residence time o...

H Tabandeh SA Mortazavi TB Guilani

A sustained-release tablet formulation should ideally have a proper release profile insensitive to moderate changes in tablet hardness that is usually encountered in manufacturing. In this study, matrix aspirin (acetylsalicylic acid) tablets with ethylcellulose (EC), Eudragit RS100 (RS), and Eudragit S100 (S) were prepared by direct compression. The release behaviors were then studied in two co...

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