نتایج جستجو برای: relaxant

تعداد نتایج: 2338  

Journal: :The Journal of pharmacology and experimental therapeutics 2007
Frederick J Ehlert Simon Ahn Kirk J Pak Grace J Park Marline S Sangnil John A Tran Minoru Matsui

We investigated whether M(2) muscarinic receptor activation opposes isoproterenol-induced relaxation in mouse urinary bladder and whether endogenous acetylcholine acts through a similar M(2) mechanism. When measured in urinary bladder from M(3) receptor knockout mice, the muscarinic agonist oxotremorine-M elicited only very weak contractions. In the presence of alpha,beta-methylene ATP (30 micr...

2016
Masoud Ghorbanlo Mahmoud Reza Mohaghegh Forozan Yazdanian Mehrdad Mesbah Ziya Totonchi

BACKGROUND The need for muscle relaxants in general anesthesia in different surgeries including cardiac surgeries, and the type of relaxant to be used considering its different hemodynamic effects on patients with heart disease can be of considerable importance. In this study, the hemodynamic effects of two muscle relaxants, Cisatracurium and Atracurium in patients whit low function of left ven...

Journal: :The journal of pain : official journal of the American Pain Society 2013
Anton A van der Plas Johanna C M Schilder Johan Marinus Jacobus J van Hilten

UNLABELLED The treatment of dystonia related to complex regional pain syndrome (CRPS) remains unsatisfactory, raising the need of alternative targets for intervention. In dystonia, pathologic muscle changes may occur, which contributes to stiffness. Because magnesium sulphate may act as a muscle relaxant through its actions on the neuromuscular junction and muscle, we performed an explanatory s...

Journal: :Advances in therapy 2008
Silvana Sartini Lucia Guerra

INTRODUCTION Eperisone hydrochloride has been recently proposed as a muscle relaxant for the treatment of muscle contracture and chronic low back pain (LBP) as it is devoid of clinically relevant sedative effects on the central nervous system (CNS). We tested this hypothesis by performing a study of patients with LBP and muscle contracture who were treated with full-dose eperisone. METHODS Pa...

Journal: :Anatolian Current Medical Journal 2022

Aim: In the endobronchial treatment of tumors that cause obstruction in tracheobronchial system; Applications such as cryo-recanalization and argon plasma coagulation (APC) are widely used. Patients presenting with central airway (CAO) require urgent intervention, sharing bronchoscopist, severe shortness breath patients, presence comorbid diseases make it difficult for anesthetists. This situat...

Journal: :Vascular pharmacology 2012
U I Aloysius F I Achike M R Mustafa

The female gender reduces the risk, but succumbs more to cardiovascular disease. The hypothesis that short-term (8weeks) Streptozotocin-induced diabetes could produce greater female than male vascular tissue reactivity and the mechanistic basis were explored. Aortic ring responses to Phenylephrine were examined in age- and sex-matched normoglycaemic/diabetic rats. The normoglycaemic male tissue...

Journal: :Hiroshima journal of medical sciences 2006
Hajime Kumagai Kazumasa Orihashi Mitsuhiro Isaka Makoto Hamaishi Taijiro Sueda

To investigate the feasibility of a novel recording method for trans-intercostal evoked spinal cord potentials (Tic-ESCPs) and the properties of the waveforms, the potentials were recorded and analyzed in an animal model. In two beagle dogs, Tic-ESCPs were recorded at the left twelfth intercostal to fourth lumbar nerves following stimulation at the left eleventh intercostal nerve, either with o...

1999
TETSUYA MATSUMOTO ATSUYUKI WADA TAKAYOSHI TSUTAMOTO TOMOKO OMURA HIROSHI YOKOHAMA MASATO OHNISHI ICHIRO NAKAE MASAYUKI TAKAHASHI MASAHIKO KINOSHITA Atsuyuki Wada Takayoshi Tsu Tomoko Omura Hiroshi Yokohama Masato Ohnishi Ichiro Nakae Masayuki Takahashi

Matsumoto, Tetsuya, Atsuyuki Wada, Takayoshi Tsutamoto, Tomoko Omura, Hiroshi Yokohama, Masato Ohnishi, Ichiro Nakae, Masayuki Takahashi, and Masahiko Kinoshita. Vasorelaxing effects of atrial and brain natriuretic peptides on coronary circulation in heart failure. Am. J. Physiol. 276 (Heart Circ. Physiol. 45): H1935–H1942, 1999.—Natriuretic peptide (NP) receptor has been postulated to be downr...

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