background: interleukin-17 (il-17), as a potent proinflammatory cytokine, has a critical role in post liver transplant outcomes. however, there is not much information about the effects of il-17 cytokine on acute liver rejection. objective: to evaluate the role of il-17 in post-liver transplant acute rejection. methods: ninety seven adult liver transplant patients who enrolled in this cross sec...

background: to evaluate vdr gene variation and its interaction with immune regulatory molecules in osteoporosis. methods: totally 205 pre and postmenopausal women were recruited in the study. after an overnight fast, peripheral blood was taken and centrifuged to sprat serum for measurement of serum parathyroid hormone, 25 hydroxyvitamin d, osteocal­cin and cross laps. the fok i polymorphism in ...

abstract potato virus s is a member of the genus carlavirus in the family of flexiviridae, with curved filamentous particles 650×12 nm and positive single stranded rna genome. this virus is one of the most common viruses that infected all of potato varieties in the world. susceptible host species belong mainly to the families solanaceae, chenopodiaceae and amaranthaceae. potato virus s transmit...

The prognosis of patients with pancreatic cancer is very poor because of late diagnosis and the lack of response to various therapies. Pancreatic cancer is generally resistant to chemotherapy and is highly fatal. Gemcitabine (GEM) appears to be the only effective agent for treatment of pancreatic cancer. However, a high level of inherent and acquired tumor resistance makes the clinical impact o...

BACKGROUND The consecutive monoculture for most of medicinal plants, such as Rehmannia glutinosa, results in a significant reduction in the yield and quality. There is an urgent need to study for the sustainable development of Chinese herbaceous medicine. METHODOLOGY/PRINCIPAL FINDINGS Comparative metaproteomics of rhizosphere soil was developed and used to analyze the underlying mechanism of...

background: acute promyelocytic leukemia (apl) is a unique subtype of acute leukemia. apl is a curable disease; however, drug resistance, early mortality, disease relapse and treatment-related complications remain challenges in apl patient management. one issue underlying these challenges is that the molecular mechanisms of the disease are not sufficiently understood. materials and methods: in ...

introduction: increased oxidative stress is widely accepted to be a factor in the development and progression of alzheimer’s disease. triazine derivatives possess a wide range of pharmacological activities including anti-oxidative and anti-in.ammatory actions. in this study, we aimed to investigate the possible protective effect of 3-thioethyl-5,6-dimethoxyphenyl-1,2,4-triazine (tedmt) on h2o2-...