A 4-year-old boy presented with vomiting and recurrent cough. He was investigated and found to have thoracic oesophageal duplication cyst. He was taken up for thoracoscopic removal of the cyst. The cyst was attached to the oesophagus and shared a common wall. The boy tolerated the procedure well and follow-up showed no recurrence of the cyst with total resolution of the symptoms. We share our e...

Hereditary angioedema is characterised by recurrent episodes of peri-orbital and peri-oral swelling which can cause an upper airway obstruction, abdominal pain, vomiting, diarrhoea, and even hypotensive collapse. This potentially fatal condition is frequently misdiagnosed; its early recognition and appropriate treatment are thus important. We report a familial cluster of hereditary angioedema i...

Introduction The daughter of a first-cousin marriage from Saudi Arabia died at age 7y/o of an unexplained periodic fever illness. At two years of age, the proband presented with recurrent fever attacks associated with febrile seizures, severe anemia, septic arthritis, diarrhea, and severe vomiting causing multiple ICU submissions. Considering her ancestry, she was thought to have an FMF-like di...

Chronic intestinal pseudo-obstruction is a rare intestinal motility disorder. It is characterized by recurrent or persistent findings of intestinal obstruction in the absence of any mechanical obstruction. Various systemic or congenital diseases are held responsible in the etiology; moreover, it is accepted as idiopathic upon failure of detection of a true reason. We present hereby two rare cas...

A 5-year-old boy had recurrent vomiting and lethargy with lacticacidemia and ketoacidemia since birth. Lipoamide dehydrogenase deficiency was found in muscle and fibroblasts. Therapy with sodium dichloroacetate, thiamine, and carnitine was associated with reduction of the severity and frequency of the decompensation episodes and near normal plasma lactate levels. At 5 years of age, the patient ...

Naphthalene, a widely used industrial and household chemical, has rarely been an agent of poisoning worldwide. Severe haemolysis from naphthalene poisoning is rare and can be a challenge to clinicians. We report a 22-year-old female, who accidentally ingested naphthalene mixed coconut oil and got admitted with recurrent vomiting, headache and passage of dark urine. Severe intravascular haemolys...

BACKGROUND Cyclic vomiting syndrome (CVS), defined by recurrent stereotypical episodes of nausea and vomiting, is a relatively-common disabling and historically difficult-to-treat condition associated with migraine headache and mitochondrial dysfunction. Limited data suggests that the anti-migraine therapies amitriptyline and cyproheptadine, and the mitochondrial-targeted cofactors co-enzyme Q1...

Aim is to discuss diagnostic and therapeutic difficulties in COVID-19 related postoperative outcomes. A 5-year-old boy operated for jejunal atresia neonatal period admitted with recurrent bilious vomiting. The upper GI series revealed dilated jejunum absence of mechanical obstruction. segment was excised anastomosis performed. Later, he developed peritonitis without signs anastomotic leaks. sec...

Cushing Syndrome, a rare condition with increased glucocorticoid production can affect renal function directly by its effect on glomerular and tubular functions or indirectly through the cardiovascular system. The aim is to report case of Syndrome complicated End Stage Renal Failure. authors present symptoms, clinical course laboratory findings 16-year-old girl diagnosis syndrome end stage fail...

Cyclic vomiting syndrome (CVS) is a chronic functional disorder characterized by episodes of severe nausea and vomiting that alternate with prolonged symptom-free intervals.1 Symptoms are often triggered by social stress; episodes can occur after the loss of a loved one, job-related stress, during exams, and even on vacations.2 The etiology of CVS is not known, but several theories have been pr...