We report three cases of effective management of infertility in women with a history of repeated unsuccessful IVF attempts, who have developed antibodies to hCG. A novel approach to conservative treatment of immunologic reproductive failure, suggested for selected patients, included membrane plasmapheresis, combined prednisolone, and intravenous immunoglobulin therapy. No adverse side effects w...

BACKGROUND Recently, the use of granulocyte colony-stimulating factor (G-CSF) has been proposed to improve pregnancy outcomes in reproductive medicine. OBJECTIVE A systematic review of the current use of G-CSF in patients who have difficulty conceiving and maintaining pregnancy was performed. MATERIALS AND METHODS Two electronic databases (PubMed/ Medline and Scopus) were searched. Study se...