The presence, frequency, and relationship of ocular and oral shedding of herpes simplex virus to previous herpes keratitis was investigated. This was to determine if a history of herpes keratitis predisposes to shedding of the herpes simplex virus into the tear film and/or mouth. Swabs were collected from the eyes and mouth of two groups of patients thrice weekly over a two- to four-month perio...

BACKGROUND The facial colliculus is an elevated area that formed by fibers from the motor nucleus of 7`th cranial nerve as they loop over abducens nucleus. Clinical signs and symptoms lesions occur primarily due to injury nucleus, around paramedian pontine reticular formation, medial longitudinal fasciculus. etiology varies age. While tumors, demyelinating lesions, viral infections can be invol...

Eritema multiforme (EM) tipik hedef lezyonlarıyla simetrik eritematöz döküntü ile karakterize, immün aracılı bir durumdur. İlaçlar, enfeksiyonlar, immünolojik durumlar ve gıda katkı maddeleri etiyolojik nedenler arasındadır, ancak Herpes simplex virus enfeksiyonu en yaygın olanıdır. labialis ilişkili üç rekürren EM olgusu sunuyoruz. Hepsi herpes döküntüsünden yaklaşık hafta sonra ortaya çıkan l...

To investigate the efficacy of corticosteroids for the treatment of herpes labialis, we compared famciclovir (Famvir, 500 mg 3x/day po [per os] for 5 days) and topical fluocinonide (0.05% Lidex Gel 3x/day for 5 days) with famciclovir and topical vehicle control for experimental ultraviolet radiation-induced herpetic recurrences. We irradiated 49 volunteers, and 29 (60%) of 48 developed signs or...

Background: Herpes simplex viruses (HSV) are human pathogens that establish lytic and latent infections. Reactivation from latency occurs intermittently, which represents a life-long source for recurrent infection. The role of immune factors in the control of recurrent symptomatic HSV lesions is complex and the exact role of cytokines remains unclear. Objective: To assess the levels of tumor ne...

The lips of 196 patients with a history of sun-induced herpes labialis were exposed to experimental ultraviolet radiation (UVR) and treated with acyclovir (ACV) or placebo at different times and by different routes. Of 98 placebo recipients, 39 (40%) developed 43 lesions inside or within 10 mm of the irradiated zone. The temporal distribution of lesions was bimodal. 11 (26%) occurring within 48...