نتایج جستجو برای: rectal administration
تعداد نتایج: 263050 فیلتر نتایج به سال:
Two methods of measuring body temperature were compared in common marmosets. Subcutaneous temperatures were measured remotely via previously implanted subcutaneous microchips (Plexx BV, IPTT-100) prior to measurement of rectal temperature using a conventional rectal probe. Marmosets were treated with saline or the brain penetrant, 5-HT1A/B/D receptor agonist SKF-99101H (3-(2-dimethylaminoethyl)...
Preoperative radiotherapy may improve the resectability and subsequent local control of rectal cancers. However, the extent of radiation induced regression in these tumours varies widely between individuals. To date no reliable predictive marker of radiation sensitivity in rectal cancer has been identified. At the cellular level, radiation injury initiates a complex molecular network of DNA dam...
Canine status epilepticus (CSE) is characterized by epileptic seizures that are longer than 5 min or more one seizure with incomplete recovery. Currently, diazepam suppositories generally prescribed for CSE. Levetiracetam (LEV) of the newest antiepileptic drugs currently available. This study compared pharmacokinetics intragastric and intrarectal administration in oral formula LEV four healthy ...
the aim of this study was to evaluate the morbidity and mortality in patients with operable stage ii and iii rectal cancers within one or two months after surgery, who has been treated pre-operatively with short course radiotherapy. twenty-eight patients with rectal adenocarcinoma, consecutively referred to the cancer institute of imam khomeini hospital from march 2009 to march 2010, were selec...
bowel stent insertion has a variety of complications one major of which is colonic perforation. the purpose of this article is to reveal two cases with delayed colonic perforation after stent placement to relieve bowel obstruction caused by rectal cancer. the first patient was a 55 year-old man who was a candidate for stent placement to avoid palliative surgery and relieve his bowel obstruction...
This study was designed to assess the safety, acceptability, pharmacokinetic (PK), and pharmacodynamic (PD) responses to rectal administration of tenofovir (TFV) 1% vaginally formulated gel and oral tenofovir disoproxil fumarate (TDF). This study was designed as a phase 1, randomized, two-site (United States), double-blind, placebo-controlled study of sexually abstinent men and women. Eighteen ...
OBJECTIVES This study was designed to assess the dose-response relationship between tissue, blood, vaginal and rectal compartment concentrations of tenofovir (TFV) and tenofovir diphosphate (TFVdp) and ex vivo rectal HIV suppression following oral tenofovir disoproxil fumarate (TDF) and rectal administration of TFV 1% vaginally-formulated gel. DESIGN Phase 1, randomized, two-site (US), double...
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