نتایج جستجو برای: receptor mediated gene transfer

تعداد نتایج: 2061574  

Journal: :Proceedings of the National Academy of Sciences 1991

Journal: :Neuron 1996
Kevin Staley Roderic Smith Jerome Schaack Christine Wilcox Thomas J Jentsch

The effect of GABAA receptor activation varies from inhibition to excitation depending on the state of the transmembrane anionic concentration gradient (delta anion). delta anion was genetically altered in cultured dorsal root ganglion neurons via adenoviral vector-mediated expression of ClC-2, a Cl- channel postulated to regulate the Cl- concentration in neurons in which GABAA receptor activat...

Journal: :Arteriosclerosis, thrombosis, and vascular biology 2009
Hiroyuki Suzuki Keita Kimura Heigoro Shirai Kunie Eguchi Sadaharu Higuchi Akinari Hinoki Kazuhiro Ishimaru Eugen Brailoiu Danny N Dhanasekaran Laura N Stemmle Timothy A Fields Gerald D Frank Michael V Autieri Satoru Eguchi

BACKGROUND Although, endothelial nitric oxide (NO) synthase (eNOS) is believed to antagonize vascular remodeling induced by the angiotensin II (AngII) type-1 receptor, the exact signaling mechanism remains unclear. METHODS AND RESULTS By expressing eNOS to vascular smooth muscle cells (VSMCs) via adenovirus, we investigated a signal transduction mechanism of the eNOS gene transfer in preventi...

2012
Weixia Ye Xueping Huang Yangyang Sun Hao Liu Jin Jiang Youde Cao

In the present study, ultrasound-mediated microbubble destruction (UMMD) alone and combined with liposome technology was used as a novel nonviral technique to transfect a Nogo receptor (Nogo-R) shRNA plasmid (pNogo-R shRNA) into neural stem cells (NSCs). Using green fluorescent protein as a reporter gene, transfection efficiency of NSCs was significantly higher in the group transfected with UMM...

2002
Nancy Larochelle Michael Famulok Waldemar Kolanus Hanns Lochmüller

Morency MJ, Larochelle N, Guay JM, Sanschagrin F, Levesque RC. Primary structure offlanking DNA sequence from the genomic dhfr-ts locus of Toxoplasma gondii. 1994:American Society for Microbiology, Las Vegas, Nevada, USA. Larochelle N., Lochmüller H., Nalbantoglu J., Jani A., Massie B., Karpati G. Muscle-specificgene expression after adenovirus-mediated gene transfer. Neurology 1996...

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