Receiver operating characteristic (ROC) analysis of nerve messages is described. The hypothesis that quantum fluctuations provide the only limit to the ability of frog ganglion cells to signal luminance change information is examined using ROC analysis. In the context of ROC analysis, the quantum fluctuation hypothesis predicts (a) the detectability of a luminance change signal should rise prop...

SUMMARY Comparison of the accuracy of two diagnostic tests using the receiver operating characteristic (ROC) curves from two diagnostic tests has been typically conducted using fixed sample designs. On the other hand, the human experimentation inherent in a comparison of diagnostic modalities argues for periodic monitoring of the accruing data to address many issues related to the ethics and ef...

Responses of brisk-sustained cat retinal ganglion cells were examined using receiver operating characteristic (ROC) analysis. Stimuli were brief luminance changes superimposed upon a weak steady pedestal ranging from 27 to 47,000 quanta (507 nm) per second at the cornea. Overall quantum efficiencies of cells ranged up to approximately 13% and were compatible with previous estimates at absolute ...

This paper presents an approach that enables automatic titling of e-mails relying on the morphosyntactic study of real titles. Automatic titling of e-mails has two interests: Titling mails ’no object’ and managing personal information. The method is developed in three stages: Candidate sentences determination for titling, noun phrases extraction in the candidate sentences, and finally, selectin...

PURPOSE To evaluate effects of combining functional magnetic resonance imaging (fMRI) data acquired from different field strengths on group analysis as a function of the number of subjects at each field strength. MATERIALS AND METHODS In all, 28 subjects (18 at 3T) participated in an auditory task of passively listening to a 0.75s segment of jazz music in an event-related design. Results of s...

The Lorenz curve for assessing economic inequality depicts the relation between two cumulative distribution functions (CDFs), one for the distribution of incomes or wealth and the other for their first-moment distribution. By contrast, the receiver operating characteristic (ROC) curve for evaluating diagnostic systems depicts the relation between the complements of two CDFs, one for the distrib...

OBJECTIVES To examine SLEDAI-2000 cut-off scores for definition of active SLE and to determine the sensitivity to change of SLEDAI-2000 for the assessment of SLE disease activity and minimal clinically meaningful changes in score. METHODS Data from two multi-centre studies were used in the analysis: in a cross-sectional and a longitudinal fashion. At every assessment, data were collected on S...

This paper clarifies two important concepts in clinical epidemiology: the slope of a receiver operating characteristic (ROC) curve and the likelihood ratio. It points out that there are three types of slopes in an ROC curve--the tangent at a point on the curve, the slope between the origin and a point on the curve, and the slope between two points on the curve. It also points out that there are...

Background Transient depressive state (TDS) is a transient, negative emotional state caused by certain events or situations. Because of the similarity in depressive symptoms between depression and TDS that arise within 2 weeks of their onset, it is difficult to distinguish TDS from depression. The aims of the present study were to investigate the application value of selected serum indicators i...

Previous studies have indicated a possible relationship between increased prostate volume (PV) and decreased biopsy yield, although the mechanism involved is unclear. We evaluated 1650 patients who underwent template biopsy. The distribution of 993 cancer lesions in 302 prostatectomy specimens was compared with the biopsy data to determine whether each lesion was detected. A receiver operating ...