Two new steroidal saponins and two known flavonoid glycosides were isolated from the fruits of Tribulus terrestris. Their structures were assigned by spectroscopic analysis and chemical reaction as 26-O-beta-D-glucopyranosyl-(25R)-5 alpha-furostan-12-one-3beta,22 alpha,26-triol-3-O-beta-D-glucopyranosyl (1 --> 2)-beta-D-glucopyranosyl(1 --> 4)-beta-D-galactopyranoside (1), 26-O-beta-D-glucopyra...

Abstract Diabetes mellitus is one of the key metabolic diseases cause due to defects in secretion insulin, insulin resistance peripheral tissues, or both. Plants remained an important source nutrition as well medicine. Stevia rebaudiana Bertoni high qualities non-caloric sugar substitute sweetener plants against diabetes disease. The compounds like steviol, rebaudioside A, stevioside, etc . can...

BACKGROUND Taste receptors are expressed not only in taste buds but also in the gastrointestinal tract. It has been hypothesized that these receptors may play a role in satiety and food intake. OBJECTIVE This study investigated the effect of intraduodenal tastant infusions (bitter, sweet, and umami) on food intake, hunger and fullness, gastrointestinal symptoms, and gastrointestinal peptide r...

Stevia rebaudiana Bertoni is famous for sweetness due to the content of steviol glycosides (SG). This study aimed determine effect SG (stevioside, rebaudioside A) and on adipogenesis lipogenesis in 3T3-L1 model. Test compounds were also analysed their ability affect glucose uptake hypertrophied insulin-resistant adipocytes. The most active compound modulating adipogenesis, insulin resistance wa...

A plant tissue culture protocol from stevia was optimized for the production of planting materials and natural sweetener, rebaudioside A. The highest survivability (88.90% ± 5.55) explants achieved at 15 30 days after initiation (DACI) on Murashige Skoog (MS) media by sterilization with 30% Clorox (5 min) 10% (10 min), respectively. Supplementation MS 0.50 mg/L 2,4-Dichlorophenoxyacetic acid (2...

Abstract In this study, the optimization and performance evaluation of a high-performance liquid chromatography with diode array detection (HPLC–DAD) method for simultaneous determination four sweeteners (acesulfame-potassium, saccharin, aspartame, rebaudioside A), two preservatives (sodium benzoate potassium sorbate), caffeine in sugar-free drinks are presented. The separation was carried out ...