Rearrangement reactions are a very powerful tool for the conversion of simple substrates into highly functionalized products in organic chemistry. In combination with an attractive initiation process, such as visible-light catalysis, these particularly powerful. Read more about recent progress on aryl migration reactions, focusing especially Smiles rearrangement and related Review by E. Brachet...

The difference between genome rearrangement theory and other approaches to comparative genomics, and indeed most other topics in computational molecular biology, is that it is not directly based on macromolecular sequences, either nucleic acids or proteins. Rather like classical genetics, its building blocks are genes, and the structures of interest are chromosomes, abstracted in terms of the l...

Gene order analysis aims at extracting phylogenetic information from the comparison of the order and orientation of the genes on the genomes of different species. This can be achieved by computing parsimonious rearrangement scenarios, i.e. to determine a sequence of rearrangements events that transforms one given gene order into another such that the sum of weights of the included rearrangement...

Mycosis fungoides (MF), the most common type of cutaneous T-cell lymphoma, has various unspecific clinical and histological characteristics. Its early diagnosis is challenging. The application of T-cell receptor (TCR) gene clonal rearrangement to the diagnosis of MF has been widely studied. In this study, we used polymerase chain reaction (PCR) to investigate the diagnostic significance of dete...

Updates of the mosaic fluid membrane model implicitly sustain paradigms that bilayers are closed systems conserving a state fluidity and behaving as dielectric slab. All them consequence disregarding water part structure its essential role in thermodynamics kinetics response to bioeffectors. A correlation thermodynamic properties with structural features makes possible introduce lipid responsiv...