MicroRNAs (miRNAs) are a class of small, non‑coding, endogenous RNAs that are important in tumor cell biological processes as they regulate gene expression. miR-195 has been demonstrated to be a tumor repressor in numerous types of human cancer. However, the mechanism by which miR‑195 suppresses tumor development remains to be elucidated. The aim of this study was to investigate the effect of m...

Activated carbon prepared from Euphorbia tirucalli L wood (ETAC) by chemical activation with phosphoric acid has been analysed for the removal of Reactive Red and Reactive Blue dyes from aqueous solutions through batch adsorption technique. Lower solution pH favours the adsorption of reactive dyes. The amount of dye adsorbed per unit mass of adsorbent increases with the increase in temperature ...

We have determined the crystal structure of the molecular complex between Streptomyces griseus protease B (SGPB), a bacterial serine protease, and the third domain of the ovomucoid inhibitor from turkey. Restrained-parameter least-squares refinement of the structure with the 1.8-A intensity data set has resulted in an R factor of 0.125. The carbonyl carbon atom of the reactive bond between Leu-...

In this research, the efficiency of electrocoagulation treatment process using iron and aluminum electrodes to treat synthetic wastewater containing Reactive Red 24 (RR 24) was studied. The effects of parameters such as current density, pH, type of electrolyte, initial dye concentration, electrolyte concentration, temperature, and inter electrode distance on dye removal efficiency were investig...

There is accumulating evidence suggesting that inflammation is the bridging link between cardiovascular disease and metabolic syndrome. Recent studies have shown a relationship between inflammatory markers and modifiable lifestyle factors including fitness, diet, exercise and smoking. We carried out a cross-sectional study of 195 patients with metabolic syndrome. Data on nutritional intake, phy...

In order to identify the inner ear autoantibodies, sera of 195 patients with sensorineural hearing loss and/or vertigo were reached with bovine inner ear antigen by western blotting method. Positive reaction was seen at several molecular weights, in which 33-35 kD, 42 kD and 68 kD were highly reactive. In moderate to severe hearing loss patients, positive reactions with 33-35 kD, 42 kD, 68 kD a...

BACKGROUND MicroRNA (miRNA) dysregulation was commonly seen in papillary thyroid carcinoma (PTC), and miR-195 was verified to be downregulated in PTC by the large data set analysis from The Cancer Genome Atlas (TCGA). Our study aimed to explore the biological functions and the underlying molecular mechanisms of miR-195 in PTC. METHODS The relative expression of miR-195 and its target genes we...