نتایج جستجو برای: reactive inhibition antibodies

تعداد نتایج: 615770  

2008
Francisco Rafael Martins Soto Sônia Regina Pinheiro Zenaide Maria Morais Amane Paldês Gonçales Sérgio Santos de Azevedo Fernanda Bernardi Sebastião Rodrigues Camargo Silvio Arruda Vasconcellos

It was performed the comparison of the intensity and duration of agglutinating and neutralizing antibodies to serovar Hardjo in swines vaccinated with two commercial anti-leptospira bacterins. Sows no reactive to 24 Leptospira sp serovars in the microscopic agglutination test (MAT) were divided in three groups: Group A (n=08): received two vaccine A doses with 30 days interval, Group B (n=08) t...

Journal: :Clinical and diagnostic laboratory immunology 2000
A Soininen G van den Dobbelsteen L Oomen H Käyhty

The specificity of antibody binding to pneumococcal capsular polysaccharides (Pnc PSs) measured by enzyme immunoassay (EIA) was studied by inhibition of antibody binding by homologous and heterologous PSs. We found extensive cross-reactivity of antibody binding to type 6B, 19F, and 23F PSs but not to type 14 PS, even after treatment with cell wall PS (CPS). The cross-reactive antibody was highl...

2016
Xiaocong Yu Mark Duval Melissa Gawron Marshall R Posner Lisa A Cavacini

Innovative strategies are necessary to maximize the clinical application of HIV neutralizing antibodies. To this end, bispecific constructs of human antibody F240, reactive with well-conserved gp41 epitope and antibody 14A8, reactive with the IgA receptor (CD89) on effector cells, were constructed. A F240 × 14A8 bispecific single chain variable region (scFv) molecule was constructed by linking ...

Journal: :International archives of allergy and immunology 2015
Christiane Hilger Ved P Dubey Delphine Lentz Caroline Davril Dominique Revets Claude P Muller Claire Diederich Hélène De La Barrière Françoise Codreanu-Morel Martine Morisset Christiane Lehners Prabir K De François Hentges

BACKGROUND An increasing number of asthma cases upon exposure to hamsters and anaphylactic reactions following hamster bites are being reported, but the allergens responsible are still poorly characterized. In the Golden hamster, male-specific submaxillary gland protein (MSP), a lipocalin expressed in a sex- and tissue-specific manner in the submaxillary and lacrimal glands, is secreted in the ...

Journal: :The Journal of clinical investigation 1975
Y Yamauchi A Litwin L Adams H Zimmer E V Hess

The antihypertensive drug hydralazine can induce in man a syndrome similar to spontaneous systemic lupus erythematosus (SLE). The pathogenesis of this drug-induced syndrome is not understood. In this investigation, five groups of rabbits were studied: group I, 10 rabbits hyperimmunized with hydralazine conjugated to human serum albumin (HSA) in complete Freund's adjuvant (CFA); group II, four r...

2011
Hua-Xin Liao Xi Chen Supriya Munshaw Ruijun Zhang Dawn J. Marshall Nathan Vandergrift John F. Whitesides Xiaozhi Lu Jae-Sung Yu Kwan-Ki Hwang Feng Gao Martin Markowitz Sonya L. Heath Katharine J. Bar Paul A. Goepfert David C. Montefiori George C. Shaw S. Munir Alam David M. Margolis Thomas N. Denny Scott D. Boyd Eleanor Marshal Michael Egholm Birgitte B. Simen Bozena Hanczaruk Andrew Z. Fire Gerald Voss Garnett Kelsoe Georgia D. Tomaras M. Anthony Moody Thomas B. Kepler Barton F. Haynes

The initial antibody response to HIV-1 is targeted to envelope (Env) gp41, and is nonneutralizing and ineffective in controlling viremia. To understand the origins and characteristics of gp41-binding antibodies produced shortly after HIV-1 transmission, we isolated and studied gp41-reactive plasma cells from subjects acutely infected with HIV-1. The frequencies of somatic mutations were relativ...

Journal: :Viruses 2021

Antibodies are a critical immune correlate of protection for rhinoviruses, particularly those antibodies found in the secretory compartment. For nonenveloped viruses such as antibody binding to regions icosahedral capsid can neutralise infections by number different mechanisms. The purpose this review is address neutralising mechanisms rhinoviruses that would help progress vaccine development. ...

Journal: :The Journal of Experimental Medicine 1984
M Edwards R L McDade G Schoolnik J B Rothbard E C Gotschlich

A bank of mouse monoclonal antibodies has been produced with reactivity to gonococcal pili to investigate epitopes of the pilus structural protein, pilin. Pili of Neisseria gonorrhoeae strains R10 and MS11 were used as immunogens to elicit 19 monoclonal antibodies reactive with the homologous pili type in ELISA. Of the 19 antibodies, 16 demonstrated type-specific reactivity and 3 were cross-rea...

Journal: :Journal of virology 1991
N Yaegashi S A Jenison J M Valentine M Dunn L B Taichman D A Baker D A Galloway

Human papillomavirus type 1 (HPV1) virions, both as intact virion particles (IVP) and as detergent-denatured virions (DDV), were used to prepare polyclonal antisera and monoclonal antibodies (MAbs) in BALB/c mice. Anti-IVP antiserum contained type-specific HPV1 L2-reactive antibodies and no detectable HPV1 L1-reactive antibodies. Anti-IVP MAbs recognized a linear epitope between L2 amino acids ...

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