Introduction: In Islamic countries in the month of Holy Ramadan many Muslims based on their religious Legislation refuse fluid intake during the fasting time though instructed to drink after injection of Tc-99m Methylene-diphosphonates [Tc-99m MDP] used for skeletal scintigraphy. We aimed to establish whether fluid restriction in Tc-99m MDP skeletal scintigraphy has an impact on its quality. M...

Macrophages and neutrophils kill the airborne fungal pathogen Aspergillus fumigatus. The dependency of this killing process on reactive oxygen intermediates (ROI) has been strongly suggested. Therefore, we investigated the enzymatic ROI detoxifying system by proteome analysis of A. fumigatus challenged by H(2)O(2). Since many of the identified proteins and genes are apparently regulated by a pu...

Hydatidosis or hydatide cyst,caused by the larvae of Echinoconccus granulosus,is one of the most serious tapeworm cestodes infection occuring in man and in livestock in Iran.the present study was carried out in order to determine the rate of infection in shahriar Area,in which no study has been conducted regarding this enfection.1052 human blood sample from different age groups were collected b...

hepatitis b is the most common cause of acute and chronic viral hepatitis in iran. it is the etiology of 70% of end-stage liver disease and hepatocellular carcinoma in the country. before the universal neonatal vaccination in iran (1992), the contact rate with hbv was about 30% and the hbs ag+ rate was about 3%. in 2009 the contact rate has declined to 18% and hbsag+ rate decreased to 2%. the e...

Background: Infectious agents have been suspected as a triggering factor for development of autoimmune thyroid disease (ATD). Some reports from Western countries have suggested association between Helicobacter pylori (HP) infection and ATD. Objective: To investigate the association of ATD with Cag A seropositivity in a population with high rate and early age of onset of HP infection. Methods: I...

To determine the relative contributions of respiratory burst-derived reactive oxygen intermediates (ROI) versus reactive nitrogen intermediates (RNI) to macrophage-mediated intracellular host defense, mice genetically deficient in these mechanisms were challenged with Leishmania donovani, a protozoan that selectively parasitizes visceral tissue macrophages. During the early stage of liver infec...