STUDY OBJECTIVE To compare spinal anesthesia and combined sciatic-femoral nerve block for outpatient knee arthroscopy. DESIGN Prospective, randomized, controlled study. SETTING Postoperative recovery area at a university-affiliated medical center. PATIENTS 50 ASA physical status I and II adult outpatients undergoing arthroscopic knee surgery. INTERVENTIONS Study subjects were equally di...

BACKGROUND Nerve conduits provide a promising strategy for peripheral nerve injury repair. However, the efficiency of nerve conduits to enhance nerve regeneration and functional recovery is often inferior to that of autografts. Nerve conduits require additional factors such as cell adhesion molecules and neurotrophic factors to provide a more conducive microenvironment for nerve regeneration. ...

ObjectiveTo determine the intraoperative and early postoperative opioid requirement after ultrasound-guided sciatic and/or femoral nerve block or epidural anaesthesia in dogs undergoing tibial plateau levelling osteotomy (TPLO).Study designProspective, masked, pilot, randomized, clinical trial.AnimalsA total of 40 client-owned TPLO.MethodsEach dog was randomly assigned to group SF (combined blo...

Direct percutaneous stimulation of the proximal sciatic nerve with a high voltage electrical stimulator was given to a patient with acute sciatic compression neuropathy. Results clearly showed a focal conduction block at the sciatic notch, which could not be precisely localised and quantified by conventional electrodiagnostic methods.

Sciatic nerve is the largest nerve in the body originating from the sacral plexus and it supplies the lower limb through its branches. It leaves the pelvic cavity and enters the gluteal region usually through the greater sciatic foramen below the piriformis. It divides into its terminal branches at various levels which determine the length of sciatic nerve. The present study is undertaken to me...

BACKGROUND Although animal studies demonstrated delayed recovery after nerve block in laboratory models of diabetes, the duration of the action of sciatic nerve blocks clinically in patients with diabetes remains to be determined. We studied the duration of a sciatic nerve block in type 2 diabetic patients compared with non-diabetic patients. METHODS We prospectively included consecutive pati...

Conduction in rat peripheral nerve has been monitored following the stimulated release of nitric oxide (NO) from diethylamine-NONOate (DEA-NONOate). Branches of the sciatic nerve were dissected, but left otherwise intact, and propagating signals recorded externally. At levels consistent with inflammation, NO exposure resulted in a complete loss of the compound action potential. Conduction was f...