RON is a receptor tyrosine kinase belonging to the MET proto-oncogene family. The purposes of this study are to determine the expression and activation of RON in a panel of human colon carcinoma cell lines. Western blotting showed that RON is barely detectable in normal and SV-40-transformed colon epithelial cells, but highly expressed and constitutively activated in several colon carcinoma cel...

Locating the optic disc center and the fovea in digital fundus images is surprisingly difficult due to the variation range in color and contrast and the possible presence of pathologies creating bright spots or changing the appearance of retinal landmarks. These reasons make it difficult to find good templates of optic disc and fovea shape and color for pattern matching. In this paper we propos...

Radial patterns of optic flow contain a centre of expansion that indicates the observer's direction of self-movement. When the radial pattern is viewed with transparently overlapping unidirectional motion, the centre of expansion appears to shift in the direction of the unidirectional motion [Duffy, C.J. & Wurtz, R.H. (1993) Vision Res., 33, 1481-1490]. Neurons in the medial superior temporal (...

Radial patterns of optic ̄ow contain a centre of expansion that indicates the observer's direction of self-movement. When the radial pattern is viewed with transparently overlapping unidirectional motion, the centre of expansion appears to shift in the direction of the unidirectional motion [Duffy, C.J. & Wurtz, R.H. (1993) Vision Res., 33, 1481±1490]. Neurons in the medial superior temporal (M...

Aromatase, the key enzyme responsible for estrogen biosynthesis, is present in the brain of all vertebrates. Much evidence has accumulated that aromatase is highly and exclusively expressed in proliferating mature radial glial cells in the brain of teleost fish even in adulthood, unlike in other vertebrates. However, the physiological significance of this expression remains unknown. We recently...

AIM To evaluate the value of quantitative diffusion tensor imaging (DTI) in assessing the axonal and myelin damage of the optic nerves and optic radiations in patients with chronic primary angle-closure glaucoma (PACG) by using high-field magnetic resonance (MR) imaging (3T). METHODS Twenty patients with bilateral chronic PACG and twenty age- and sex matched disease-free control subjects were...