The pyrolytic behaviour of (-)-(S)-nicotine in methanol was investigated using on-line pyrolysis GC/MS to establish whether racemization to the R(+) antipode occurs and to identify other products of pyrolysis. The conditions used included pyrolysing the sample for 15 seconds in an atmosphere of 9% oxygen in nitrogen (275 ml/min total flow) across the temperature range of 200 degrees C-1000 degr...

An automated microflow measurement system for the kinetic study of racemization dynamic chiral molecules was developed. This facilitated analysis fast within several seconds at elevated temperatures owing to its rapid heating ability, high performance controlling short residence times, and ease connection HPLC systems direct enantiomeric purity. A more precise realized by combination common bat...