background wound healing is a complicated and integrated process. researches have indicated the wound healing effects of calcium channel blockers in animal models in recent years. objectives the aim of this study was to evaluate the wound-healing activity of amlodipine as a calcium channel blocker and combination of amlodipine with phenytoin on excisional cutaneous wound models in rabbit. mater...

Background Measurement of arterial blood pressure is recommended in anaesthetized animals to guide perioperative treatment. Invasive measurement considered the gold standard, however it also technically challenging, requires specialised equipment and carries certain risks. For these reasons, non-invasive devices are commonly used expected provide accurate reliable results. This requirement part...

Background: Skin is the largest organ in body and performs a wide variety of different function. It play an important role injury skin. Burns (Dagdha Vrana) are significant health challenge healing can result scar formation. Within herbal medicine tradition concept Tonification Trophorestoration well established. Concepts regeneration Ayurveda provide another dimension to area regenerative medi...

Abstract Tuberculosis (TB), the disease caused by Mycobacterium tuberculosis (Mtb), remains major health problem. We performed experiments with rabbits infected a novel, virulent clinical Mtb isolate of Beijing lineage HN878 carrying an unstable plasmid pBP10, allowing us to quantify how quickly replicates and dies in lungs rabbits. In our vitro we found that pBP10 is more stable strain than co...


 Purpose: To investigate the effect of Zhitong Jiangu decoction (ZJD) on osteoarthritis rabbits, and mechanism action involved.
 Methods: Chondrocytes were obtained from knees osteoarthritic rabbits. These chondrocytes randomly assigned to 7 groups: sham, 5, 10 20 % normal serum groups; 5 ZJD, ZJD groups. The gross histopathological features rabbit cartilage examined by microscopy. E...

Eimeria intestinalis infects rabbits, causing severe intestinal coccidiosis. Prolonged anticoccidial drug use might lead to coccidia resistance and residues in food. Thus, vaccines are required control rabbit In this study, recombinant E. 14-3-3 GRA10 proteins (rEi-14-3-3 rEi-GRA10) were obtained via prokaryotic expression used as subunit vaccines. Fifty 30-day-old rabbits randomly grouped foll...

Introduction . The use of fluoroquinolones is associated with prolongation the QT interval on cardiogram and increased risk ventricular tachycardia. To study mechanism cardiotoxic effect to develop methods its prevention it necessary create models laboratory animals. aim work was analyze electrocardiographic parameters rabbits. Materials 20 rabbits were divided into 3 groups: 6 animals control,...

Rabbits are commonly used for pharmacokinetic (PK) and toxicokinetic (TK) studies in the research setting, requiring repetitive venipuncture, which can be challenging this species. The auricular vessels venipuncture rabbits. access of these delicate lead to trauma such as hematomas causing become more study progresses. In turn, leads missed time points or insufficient blood samples. Surgical mo...

The maternal form of modern rabbit crosses is obtained by crossing ancestral lines. Therefore it relevant to investigate the effect using males parental line Hyla cross with different weight indices on performance main breeding traits female rabbits cross. purpose study was level productivity reproduction signs and consider dynamics for a number births. experiments used 223 cross, which came fr...

The immune response against Staphylococcus epidermidis, as determined by an enzyme-linked immunosorbent assay, was evaluated in experimental S. epidermidis infections in rabbits. Antigens from 8 of 10 clinical S. epidermidis strains detected significant antibody production in five rabbits immunized with different strains of S. epidermidis and in five of six rabbits with experimental endocarditi...