Since the seminal production of Noblit and Hares’ book Meta-ethnography published in 1988, the quest for an optimal route to synthesising qualitative evidence has gained momentum. Theoretical arguments in this area range diametrically from the impossibility of progressing knowledge based on qualitative evidence in the absence of such synthesis, to the impossibility of synthesising knowledge tha...

BACKGROUND Psychosocial interventions can improve behaviour and mood in people with dementia, but it is unclear how to maximise their effectiveness or acceptability in residential settings. AIMS To understand what underlies the successful implementation of psychosocial interventions in care homes. METHOD Systematic review and meta-synthesis of qualitative research. RESULTS The synthesis o...

BACKGROUND There is a growing recognition of the value of synthesising qualitative research in the evidence base in order to facilitate effective and appropriate health care. In response to this, methods for undertaking these syntheses are currently being developed. Thematic analysis is a method that is often used to analyse data in primary qualitative research. This paper reports on the use of...

Clinical decision-making requires synthesis of evidence from literature reviews focused on a specific theme. Evidence synthesis is performed with qualitative assessments and systematic reviews of randomized clinical trials, typically covering statistical pooling with pairwise meta-analyses. These methods include adjusted indirect comparison meta-analysis, network meta-analysis, and mixed-treatm...

Using oocytes isolated from juvenile and adult mice, we have examined the qualitative patterns of protein synthesis during growth and during meiotic maturation of these oocytes. Oocytes were cultured in a denned medium in the presence of [^Slmethionine and radioactively labelled proteins were separated by SDS-polyacrylamide gel electrophoresis and detected by fluorography. The results of these ...

This paper discusses the synthesis of qualitative data during the systematic review of interpretive research. Current approaches to data synthesis can be broadly classified as either descriptive or interpretive. Descriptive data synthesis is achieved through narrative and tabulation. While a number of different terms have been used, interpretive synthesis is achieved through processes similar t...

INTRODUCTION Osteoarthritis is a highly prevalent and disabling condition. Primary care management of osteoarthritis is generally suboptimal despite evidence for several modestly effective interventions and the availability of high-quality clinical practice guidelines. This report describes a planned study to synthesise the views of primary care clinicians on the barriers and enablers to follow...

INTRODUCTION This protocol aims to describe the objective and methods to be followed in a systematic review of qualitative studies on barriers and facilitators to physical activity (PA) in people with hip or knee osteoarthritis (OA). METHODS AND ANALYSIS MEDLINE, EMBASE, PhychINFO, Web of Science, CINAHL, SPORTDiscus, Scopus and grey literature sources will be electronically searched. Hand se...

CONTEXT Systematic reviews of qualitative research studies extend understanding of health care beyond effectiveness to acceptability and user views. OBJECTIVE The paper surveys reports of qualitative systematic reviews and, by characterizing techniques used to identify articles for inclusion, proposes standards for reporting of literature searches. DATA SOURCES AND STUDY SELECTION A search ...