We reported previously the characterization of Pax-QNR/Pax-6 products expressed in the avian neuroretina. Five proteins (48, 46, 43, 33, and 32 kDa) were characterized, among which the 33 and 32 kDa proteins are devoid of the paired domain. In contrast to the 48-kDa (containing an alternative paired exon 4a) and 46-kDa proteins exclusively located in the nucleus, the 43- (in which the paired ex...

additive effect on quinolone susceptibility.7 Though Qnr proteins and Aac(60)-Ib-cr only induce low level quinolone resistance, they are known to facilitate selection of resistancemutations in the presence of concentrations of quinolone antibiotics.8 We describe an isolate of K. pneumoniae isolate carrying three plasmid-mediated quinolone-resistant genes (qnrB, qnrS and aac (60)-Ib-cr variant) ...

BACKGROUND Acute infectious diarrhea is one of the most important causes of morbidity and mortality worldwide. OBJECTIVES The objective of this study was to characterize antimicrobial resistant diarrheagenic Escherichia coli strains isolated from diarrheic children in Tehran, IR Iran. PATIENTS AND METHODS In total, 550 stool samples from diarrheic pediatric patients, aged less than 60 month...

OBJECTIVES The aim of this study was to characterize fluoroquinolone-resistant Shigella and determine whether the qnr and aac(6')-Ib-cr genes could contribute to sporadic shigellosis at the clinic in the Hangzhou area of China. METHODS A total of 202 strains of Shigella (79 Shigella sonnei and 123 Shigella flexneri ) isolated from sporadic cases of shigellosis from 1998 to 2007 were analysed ...