4-Hydroxy-2-keto-pentanoic acid aldolase from Escherichia coli was identified as a class I aldolase. The enzyme was found to be highly selective for the acetaldehyde acceptor but would accept alpha-ketobutyric acid or phenylpyruvic acid in place of the pyruvic acid carbonyl donor.

NAD-dependent l- and d-lactate dehydrogenases coexist in Lactobacillus genomes and may convert pyruvic acid into l-lactic acid and d-lactic acid, respectively. Our findings suggest that the relative catalytic efficiencies of ldhL- and ldhD-encoded products are crucial for the optical purity of lactic acid produced by Lactobacillus strains.

In a previous paper it was shown (Allibone and Fich, 1946) that toxic and infective states raised the blood pyruvic acid level in spite ofwhat normally would have been an adequate thiamine intake. Ihis phenomenon was particularly noticeable in infancy. Two factors had now to be considered The first was whether the vitamin was being absorbed. Diarrhoea, which obviously would interfere with absor...

The accurate determination of pyruvic and lactic acids is a matter of considerable theoretical and practical importance. These acids play a role in the metabolism of carbohydrates, and they are found in increased concentration in the blood in conditions of thiamine deficiency. Recently we suggested (1) the determination of the ratio of lactic to pyruvic acid in the blood as a measure of oxidati...

BACKGROUND Pyruvic acid is an alpha-keto acid that presents keratolytic, antimicrobial, and sebostatic properties as well as the ability to stimulate new collagen production and elastic fibers formation. Because of its low pKa and its small dimension, it penetrates rapidly and deeply through the skin, so far as to be considered a potent chemical peel agent. It has proven its efficacy for the tr...

effect of different amounts of sulfur fertilizer (0, 50, 100, 150, 200, 250 kg/ha) and 200 kg/ha of thiobacillus inoculant on yield, quality and storability of two edible onion cultivars red rey and white qom were investigated. the experiments were conducted at experimental field and laboratories of the department of horticulture, seed and plant improvement institute, karaj, iran in 2007-08 cro...