background: to manage relapsing‑remitting multiple sclerosis (ms) in the course of acute exacerbations, methylprednisolone (mp) (medrol or solu‑medrol), has the ability to lock the injured blood‑brain barrier and decrease irritation in the central nervous system. the aim of this preliminary study was to investigate the frequency and time interval related to mp pulse therapy in patients with ms....

In this study, the effects of the second pulse resistance spot welding on the microstructure and mechanical properties of TRIP1100 steel were evaluated. The thermal process after welding was designed to improve metallurgical properties with pulse currents of 6kA, 9kA and 12kA after initial welding with 10kA current. The effect of the second pulse on mechanical and microstructural properties was...

The effects of pulse rate on absolute threshold ~THS!, maximum acceptable loudness ~MAL!, and dynamic range ~DR! were evaluated in 15 Clarion cochlear implant users. A wider range of pulse rates was assessed than in previous studies, and subjects with both standard and perimodiolar electrode arrays were tested. THS and MAL decreased with pulse rate, and DR increased with pulse rate, for pulse r...

In twelve anaesthetised, ventilated dogs the effects of hypercapnia and pharmacologically induced arterial hypotension and hypertension on the interrelation between volume-pressure response (VPR) and cerebro-spinal fluid (CSF) pulse pressure were studied during continuous inflation of a supratentorial extradural balloon. Hypercapnia did not significantly affect the intracranial volume-pressure ...

Objective: Pemphigus vulgaris, a fatal autoimmune mucocutaneous disorder commonly seen involving the oral cavity, has since a long time remained a topic of concern regarding its treatment modalities. Pulse therapy, introduced in 1984, employs high-dose corticosteroids along with certain immunosuppressive agents and has gained wide popularity since the last three decades due to its advantage of ...

OBJECTIVE To compare the efficacy and side effects of intermittent pulse cyclophosphamide plus methylprednisolone with continuous oral cyclophosphamide plus prednisolone, followed by azathioprine, in patients with proliferative glomerulonephritis caused by systemic lupus erythematosus (SLE). METHODS A multicentre randomised controlled trial was conducted between June 1992 and May 1996 involvi...

Laser parameters, typically wavelength, pulse width, irradiance, repetition rate, and pulse energy, are critical parameters which influence the laser ablation process and thereby influence the LA-ICP-MS signal. In recent times, femtosecond laser ablation has gained popularity owing to the reduction in fractionation related issues and improved analytical performance which can provide matrix-inde...

Fatigue is synonymous with a wide spectrum of familiar physiological conditions, from pathology and general health, to sport and physical exercise. Strenuous, prolonged exercise training causes fatigue. Although several studies have investigated the effects of electrical stimulation frequency on muscle fatigue, the effects of percutaneous pulse current stimulation on fatigue in the hepatic tiss...

n order to perform highspeed digital communications we have to necessarily reduce of the pulse width and thereby increase the information rate that can be transmitted and this technique offers the potential for faster computational devices. It is expected that when the pulse width becomes shorter, our ability to accurately model the propagation of the pulse will become more complicated. With a ...

Background: Pulse therapy is a type of systemic management in which large amounts of medications are administered to patients in short time and intervals (e.g. weekly) to get the stronger effects of medication sooner and avoid long term use of them. Objective: To determine how therapy-resistant dermatology diseases respond to oral minipulse steroids . Methods: Articles with Mesh terms "pulse th...