Small cell lung cancer is a common type of lung cancer that is generally classified within the spectrum of neuroendocrine lung neoplasms. Using high-density cDNA arrays, we profiled gene expression of small cell lung cancers and compared these expression profiles to those of normal bronchial epithelial cells and pulmonary carcinoids, which are classified as benign neuroendocrine tumors. We foun...

In contrast to the now frequently appearing and diagnosed pulmonary and bronchial carcinomata, primary tumors of the pleura are rare. Clinical differentiation of malignant tumors of the pleura from malignant tumors of the lung is essential. The most common malignant tumors of the pleura are the endotheliomata, the course of which resembles the course of an exudative tuberculous pleurisy. Benign...

BACKGROUND Intrapulmonary carcinoid tumors (ICTs) are malignant, slow-growing tumors classified as either: i) typical, less aggressive, well-differentiated tumors or ii) atypical, more aggressive, poorly-differentiated tumors. Most typical carcinoid tumors originate in the central airway and present with symptoms related to bronchial obstruction. In contrast, atypical carcinoids tend to occur m...

Introduction Primary cardiac tumors are extremely rare, found in only 0.02% of all autopsies. These malignant 25% the cases, 75% which sarcomas, frequently affecting young people with no risk factors.² The median overall survival is less than 1 year,³ ranging from 9 to 16 months,, rapid proliferation and deaths caused by arrhythmias, thrombosis, pulmonary embolism, and, most importantly, heart ...

A 30 years old male patient was referred to our hospital with a diagnosis of pulmonary thromboembolism due to thorax-computerized tomography (CT) angiography, revealing a thrombus totally occluding left main pulmonary artery. The lesion was evaluated as tumoural mass. Positron emission tomography (PET)-CT revealed pathologic uptake at pulmonary artery mass. Due to localization of tumour, left p...

metastatic tumors to the heart unlike primary cardiac tumors are not rare. despite its frequency, cardiac metastasis is commonly detected only during autopsy as the symptoms of disseminated metastasis prevail over symptoms caused by cardiac metastasis and hence is overlooked most of the time. tumors more commonly found metastasizing to the heart are malignancies of lung, breast, esophagus, lymp...

Abstract Background Pulmonary metastasectomy was performed in the early twentieth century and ever since, it has evolved to be one of main treatment options for certain metastatic malignancies. The advancement minimally invasive procedures enabled new techniques minimize morbidity improve patient quality care overall outcome. Cases presentation Herein we present three patients, aged 53, 48, 27 ...

We encountered an extremely rare case of multiple pulmonary sclerosing hemangiomas (PSH) with extensive neuroendocrine lesions, including pulmonary neuroendocrine cell (PNC) hyperplasia, multiple carcinoid tumorlets and typical carcinoid tumors within one pulmonary lobe. To the best of our knowledge, this is the first reported case in the English medical literature of PSH combined and admixed w...

Objective: To improve the postoperative results of limited resection for small lung cancer, we have developed a new operative method, pulmonary artery-guided segmentectomy. This resection begins with identification of the pulmonary arterial branches involved in the tumor, then the pulmonary tissue is divided along the pulmonary arteries (i.e. guided by pulmonary arteries) from the hilum toward ...

pulmonary arteriovenous malformations are rare clinical entities thai are associated with right to left shunts, and are often clinically presented by the triad of dyspnea, cyanosis, and digital clubbing. currently, transcatheter embolization of fistula is gaining increasing popularity as the superior therapeutic option. in certain situations, however, surgery is preferred. two cases of direct p...